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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chemical Compound Review: 

CHEMBL81721     2,4,6-triiodophenol

Synonyms: SureCN338137, NSC-2594, AG-C-83407, ACMC-209mn9, ANW-33619, ...
 
 
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High impact information on NSC 2594

  • In addition, the nonnative ligand 2,4,6-triiodophenol, which binds to TTR with slightly increased affinity also inhibits TTR fibril formation by this mechanism [1].
  • 3,3',5-Trichlorobisphenol A and 2,4,6-triiodophenol acted as T3 antagonists in the X. laevis tadpole metamorphosis assay [2].
 

Analytical, diagnostic and therapeutic context of NSC 2594

  • A rapid and simple HPLC method is described for the determination of Bobel-24 (2,4,6-triiodophenol) and other iodinated derivatives in biological samples [3].

References

  1. Inhibiting transthyretin amyloid fibril formation via protein stabilization. Miroy, G.J., Lai, Z., Lashuel, H.A., Peterson, S.A., Strang, C., Kelly, J.W. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  2. In vitro and in vivo analysis of the thyroid disrupting activities of phenolic and phenol compounds in Xenopus laevis. Kudo, Y., Yamauchi, K. Toxicol. Sci. (2005) [Pubmed]
  3. High-performance liquid chromatography analysis of Bobel-24 in biological samples for pharmacokinetic, metabolic and tissue distribution studies. García-Capdevila, L., López-Calull, C., Pompermayer, S., Arroyo, C., Molins-Pujol, A.M., Bonal, J. J. Chromatogr. B Biomed. Sci. Appl. (1998) [Pubmed]
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