Chemical Compound Review:
DMP728 (4R,7S,13R)-7-[3- (diaminomethylideneamino)...
Synonyms:
XL118, LS-173477, AC1L3TI7, C25H36N8O7.CH4O3S
This record was replaced with 121845.
- Oral antiplatelet, antithrombotic efficacy of DMP 728, a novel platelet GPIIb/IIIa antagonist. Mousa, S.A., DeGrado, W.F., Mu, D.X., Kapil, R.P., Lucchesi, B.R., Reilly, T.M. Circulation (1996)
- Antiplatelet and antithrombotic efficacy of DMP 728, a novel platelet GPIIb/IIIa receptor antagonist. Mousa, S.A., Bozarth, J.M., Forsythe, M.S., Jackson, S.M., Leamy, A., Diemer, M.M., Kapil, R.P., Knabb, R.M., Mayo, M.C., Pierce, S.K. Circulation (1994)
- Correlation between the in vivo efficacy of GPIIb/IIIa receptor antagonists (m7E3, MK-383 and DMP-728) and ex vivo platelet inhibition. Huang, J., Rebello, S.S., Faul, J.D., Lucchesi, B.R. Pharmacology (1999)
- Pharmacodynamics and pharmacokinetics of DMP 728, a platelet GPIIb/IIIa antagonist, in healthy subjects. Michaelis, W., Turlapaty, P., Gray, J., Fiske, W.D., Faulkner, E., Kornhauser, D., Mousa, S.A. Clin. Pharmacol. Ther. (1998)
- Prodrug and analog approaches to improving the intestinal absorption of a cyclic peptide, GPIIb/IIIa receptor antagonist. Saitoh, H., Aungst, B.J. Pharm. Res. (1997)
- The effect of absorption enhancers on the oral absorption of the GP IIB/IIIA receptor antagonist, DMP 728, in rats and dogs. Burcham, D.L., Aungst, B.A., Hussain, M., Gorko, M.A., Quon, C.Y., Huang, S.M. Pharm. Res. (1995)
- Intravenous antiplatelet efficacy and safety of the platelet GPIIb/IIIa antagonist, DMP 728 in anesthetized dogs. Mousa, S.A., Flint, S., Lorelli, W., Hassell, S., Bozarth, J., De Grado, W., Reilly, T.M. Thromb. Res. (1994)
- A monoclonal antibody that recognizes the GPIIb/IIIa antagonist DMP 728. Reversal of the effects of DMP 728 on platelet aggregation and bleeding time in the dog. Reilly, T.M., Mousa, S.A., Racanelli, A.L., Thoolen, M.J., Flint, S.K., Bozarth, J.M., Mu, D.X., Walton, H.L. Arterioscler. Thromb. Vasc. Biol. (1995)
- Simultaneous quantification of seven active metabolites of roxifiban in human plasma by LC/MS/MS in the presence of an interfering displacer at millimolar concentrations. Shi, G., Lloyd, T.L., Sy, S.K., Jiao, Q., Wernicki, A., Mutlib, A., Emm, T.A., Unger, S.E., Pieniaszek, H.J. Journal of pharmaceutical and biomedical analysis. (2003)
- Platelet GPIIb/IIIa receptor occupancy studies using a novel fluoresceinated cyclic Arg-Gly-Asp peptide. Tsao, P.W., Bozarth, J.M., Jackson, S.A., Forsythe, M.S., Flint, S.K., Mousa, S.A. Thromb. Res. (1995)
- Determination of DMP 728, a IIb/IIIa receptor antagonist, in rat and dog plasma by high-performance liquid chromatography with fluorimetric detection. Wu, S.T., Stampfli, H.F., Banks, C.M., Emm, T.A., Kapil, R.P., Padovani, P.K., Lee, W.M., Huang, S.M. J. Chromatogr. B, Biomed. Appl. (1994)