Chemical Compound Review:
Efaproxyn 2-[4-[(3,5-dimethylphenyl) carbamoylmethyl]...
Synonyms:
Efaproxiral, RSR-13, RSR-56, RSR13, CHEMBL18901, ...
- Phase II multicenter study of induction chemotherapy followed by concurrent efaproxiral (RSR13) and thoracic radiotherapy for patients with locally advanced non-small-cell lung cancer. Choy, H., Nabid, A., Stea, B., Scott, C., Roa, W., Kleinberg, L., Ayoub, J., Smith, C., Souhami, L., Hamburg, S., Spanos, W., Kreisman, H., Boyd, A.P., Cagnoni, P.J., Curran, W.J. J. Clin. Oncol. (2005)
- Efaproxiral red blood cell concentration predicts efficacy in patients with brain metastases. Stea, B., Shaw, E., Pintér, T., Hackman, J., Craig, M., May, J., Steffen, R.P., Suh, J.H. Br. J. Cancer (2006)
- Whole-brain radiotherapy with or without efaproxiral for the treatment of brain metastases: Determinants of response and its prognostic value for subsequent survival. Stea, B., Suh, J.H., Boyd, A.P., Cagnoni, P.J., Shaw, E. Int. J. Radiat. Oncol. Biol. Phys. (2006)
- Efaproxiral: a radiation enhancer used in brain metastases from breast cancer. Charpentier, M.M. The Annals of pharmacotherapy. (2005)
- Using exposure-response and biomarkers to streamline early drug development. Venitz, J. Ernst Schering Res. Found. Workshop (2007)
- Efaproxiral (RSR13) plus oxygen breathing increases the therapeutic ratio of carboplatin in EMT6 mouse mammary tumors. Donnelly, E.T., Liu, Y., Rockwell, S. Exp. Biol. Med. (Maywood) (2006)
- Cerebral metastases--a therapeutic update. Cavaliere, R., Schiff, D. Nature clinical practice. Neurology. (2006)
- Increased oxygenation of intracranial tumors by efaproxyn (efaproxiral), an allosteric hemoglobin modifier: In vivo EPR oximetry study. Hou, H., Khan, N., O'Hara, J.A., Grinberg, O.Y., Dunn, J.F., Abajian, M.A., Wilmot, C.M., Demidenko, E., Lu, S., Steffen, R.P., Swartz, H.M. Int. J. Radiat. Oncol. Biol. Phys. (2005)