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Chemical Compound Review: 

CPD-8145     1-nitrobutane

Synonyms: NSC-3648, ACMC-1B060, CCRIS 3089, NSC3648, LS-1506, ...
 
 
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High impact information on CCRIS 3089

  • The V/K values for primary nitroalkanes increase with increasing chain length, reaching a maximum with 1-nitrobutane [Gadda, G., and Fitzpatrick, P. F. (1999) Arch. Biochem. Biophys. 363, 309-313] [1].
  • The V/K values for primary nitroalkanes increase with increasing length of the alkyl chain, reaching a maximum with 1-nitrobutane, suggesting a hydrophobic binding site sufficient to accommodate a four carbon chain [2].

References

  1. Use of pH and kinetic isotope effects to dissect the effects of substrate size on binding and catalysis by nitroalkane oxidase. Gadda, G., Choe, D.Y., Fitzpatrick, P.F. Arch. Biochem. Biophys. (2000) [Pubmed]
  2. Substrate specificity of a nitroalkane-oxidizing enzyme. Gadda, G., Fitzpatrick, P.F. Arch. Biochem. Biophys. (1999) [Pubmed]
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