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Chemical Compound Review:

N-Nor-cit methyl (1R)-3-(4-iodophenyl)-8...

Synonyms: Nor-beta-cit, AC1L306Z, 136794-87-1

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High impact information on Nor-beta-cit

In conclusion, nor-beta-CIT binds to the serotonin transporter in the primate brain in vitro and in vivo and has potential for PET and SPET imaging of the serotonin transporter in human brain [1].
The comparison of the volumes of distribution did not show significant differences between the patients and controls in the binding of nor-beta-CIT to 5-HTT in the ROI [2].

Associations of Nor-beta-cit with other chemical compounds

In vitro and in vivo characterisation of nor-beta-CIT: a potential radioligand for visualisation of the serotonin transporter in the brain [1].

Analytical, diagnostic and therapeutic context of Nor-beta-cit

Deep serotonergic and dopaminergic structures in fetal alcoholic syndrome: a study with nor-beta-CIT-single-photon emission computed tomography and magnetic resonance imaging volumetry [3].

References

In vitro and in vivo characterisation of nor-beta-CIT: a potential radioligand for visualisation of the serotonin transporter in the brain. Bergström, K.A., Halldin, C., Hall, H., Lundkvist, C., Ginovart, N., Swahn, C.G., Farde, L. European journal of nuclear medicine. (1997) [Pubmed]
SPECT imaging of serotonin transporter binding in patients with generalized anxiety disorder. Maron, E., Kuikka, J.T., Ulst, K., Tiihonen, J., Vasar, V., Shlik, J. European archives of psychiatry and clinical neuroscience. (2004) [Pubmed]
Deep serotonergic and dopaminergic structures in fetal alcoholic syndrome: a study with nor-beta-CIT-single-photon emission computed tomography and magnetic resonance imaging volumetry. Riikonen, R.S., Nokelainen, P., Valkonen, K., Kolehmainen, A.I., Kumpulainen, K.I., Könönen, M., Vanninen, R.L., Kuikka, J.T. Biol. Psychiatry (2005) [Pubmed]

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