Disease relevance of Ametryn

• Analysis and toxicity of methomyl and ametryn after biodegradation [1].

High impact information on Ametryn

• We report a joint computational and luminescence study on the low-lying excited states of sym-triazines, namely, 1,3,5-triazine (1) and the ubiquitous herbicides atrazine [6-chloro-N2-ethyl-N4-isopropyl-1,3,5-triazine-2,4-diamine (2)] and ametryn [6-methylthio-N2-ethyl-N4-isopropyl-1,3,5-triazine-2,4-diamine (3)] [2].
• Hydrolysis of ametryn sulfoxide by TrzN, both in vitro and in vivo, yielded a product(s) that reacted with 7-chloro-4-nitrobenz-2-oxa-1,3-diazole (NBD-Cl) to generate a diagnostic blue product [3].
• RESULTS: Between 1981 and 1993, diagnostic or therapeutic access to the biliary or pancreatic duct system was attempted in 2105 patients by means of EST or related procedures (period A 1093 patients; period B 1012 patients) [4].
• The importance of polar interactions for ametryn sorption was evaluated by normalizing sorption to an "inert" solvent, n-hexane. n-Hexane-normalized sorption of ametryn was much greater than that of phenanthrene, presumably due to ametryn participation in hydrogen bonding interactions [5].
• The results obtained by chemical and bioassay analysis for the degradation rates of chlorotoluron, ametryn, 2,4-D and C 19490 showed a correlation coefficient of 0.914, indicating that the two methods gave almost identical results [6].

Biological context of Ametryn

• For ametryn and diuron formulations, because of the lower aqueous solubility of these herbicides, it was necessary to model a stagnant film at the formulation surface to describe better the release kinetics because the model incorporating sink conditions is insufficient [7].
• The aim of our study was the induction of sister chromatid exchanges (SCE) in human lymphocytes in vitro and in root tip meristems of Vicia faba to evaluate the genotoxic effects of metribuzin and ametryn [8].

Associations of Ametryn with other chemical compounds

• Metribuzin and ametryn applied to V. faba root tip meristems for 4 h increased SCE frequency significantly, and a concentration-response relationship was observed with both herbicides [8].
• Liquid chromatography-mass spectrometry (LC-MS) was used to determine final pesticide concentrations and for metabolite identification.The efficiency of aerobic biodegradation of ametryn and methomyl was evaluated by measuring both the decrease in the concentration of the pesticides and global properties such as the chemical oxygen demand (COD) [1].
• DDD, DDE and ametryn were the most frequently detected pesticides in sediment in the St [9].
• But the pH effect was totally neutralized and the adsorption of ametryn was significantly reduced by further addition of ferric ion, demonstrating the existence of the weak interaction between ametryn and ferric acid [10].
• Multiple regression analysis showed that Kd values were better correlated (r2=0.94 and 0.89 for ametryn and imazethapyr, respectively) if SOC and pH were simultaneously taken into account [11].

Analytical, diagnostic and therapeutic context of Ametryn

• Gas chromatographic and mass spectrometric properties of ametryn and its N-dealkylated products were studied to establish the potential use in a recently reported method describing the residue analyses of these compounds by gas chromatography with N-P detection [12].

References