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Chemical Compound Review:

Lopac-A-162 1-aminocyclohexane-1- carboxylic acid

Synonyms: PubChem13882, SureCN59793, CHEMBL559934, NSC-9059, ACMC-1CLFV, ...

Jastrzebska, B. et al., Aoyagi, M. et al., Kowalczyk, W. et al.

Kowalczyk, Prahl, Derdowska, Dawidowska, Slaninová, Lammek,

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High impact information on Lopac-A-162

Highly potent 1-aminocyclohexane-1-carboxylic acid substituted V2 agonists of arginine vasopressin [1].
Blood-brain barrier transport of 1-aminocyclohexanecarboxylic acid, a nonmetabolizable amino acid for in vivo studies of brain transport [2].

Associations of Lopac-A-162 with other chemical compounds

Influence of 1-aminocyclohexane-1-carboxylic acid in position 2 or 3 of AVP and its analogues on their pharmacological properties [3].

Gene context of Lopac-A-162

In this study we describe the synthesis and some pharmacological properties of seven new analogues of arginine vasopressin (AVP) substituted in position 2 or 3 with 1-aminocyclohexane-1-carboxylic acid (Acc) [3].

References

Highly potent 1-aminocyclohexane-1-carboxylic acid substituted V2 agonists of arginine vasopressin. Kowalczyk, W., Prahl, A., Derdowska, I., Dawidowska, O., Slaninová, J., Lammek, B. J. Med. Chem. (2004) [Pubmed]
Blood-brain barrier transport of 1-aminocyclohexanecarboxylic acid, a nonmetabolizable amino acid for in vivo studies of brain transport. Aoyagi, M., Agranoff, B.W., Washburn, L.C., Smith, Q.R. J. Neurochem. (1988) [Pubmed]
Influence of 1-aminocyclohexane-1-carboxylic acid in position 2 or 3 of AVP and its analogues on their pharmacological properties. Jastrzebska, B., Derdowska, I., Kowalczyk, W., Machova, A., Slaninová, J., Lammek, B. J. Pept. Res. (2003) [Pubmed]

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