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Chemical Compound Review

Bramazil     (E)-N,6,6-trimethyl-N- (naphthalen-1...

Synonyms: Corbinal, Terbinex, Lamasil, Lamisil, TerbiFoam, ...
 
 
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Disease relevance of Lamisil

 

Psychiatry related information on Lamisil

 

High impact information on Lamisil

  • The quadruple mutant, however, was more sensitive to terbinafine, an inhibitor of Erg1p, than the are1are2 strain suggesting that the presence of TAG and/or intact lipid particles has an additional protective effect [11].
  • Overexpression/selection using the sterol synthesis inhibitors terbinafine (TBF, targeting squalene epoxidase) and itraconazole (ITZ, targeting lanosterol C(14)-demethylase) yielded nine new resistance loci [12].
  • Rat SE cDNA was isolated by selecting yeast transformants expressing rat cDNA in the presence of transformants expressing rat cDNA in the presence of terbinafine, an inhibitor specific for fungal SE [13].
  • (vi) Treatment of S. cerevisiae with azole or terbinafine resulted in transcriptional upregulation of genes FKS2 and PMR1 known to be Ca2+ regulated [14].
  • Terbinafine hepatotoxicity resulting in chronic biliary ductopenia and portal fibrosis [15].
 

Chemical compound and disease context of Lamisil

 

Biological context of Lamisil

 

Anatomical context of Lamisil

 

Associations of Lamisil with other chemical compounds

 

Gene context of Lamisil

 

Analytical, diagnostic and therapeutic context of Lamisil

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