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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chemical Compound Review: 

Cembrane     1,7,11-trimethyl-4-propan-2- yl...

Synonyms: Cembrane I, CHEBI:60689, AC1L26G9, 1786-12-5
 
 
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High impact information on Cembrane

  • Structure-related inhibitory effects on the prostaglandin synthesis in vitro have been detected among eight diterpenoids of the cembrane class (1-8) [1].
  • Two new cembrane-type diterpenoids have been isolated from the 2-propanol extract of the sea pen Gyrophyllum sibogae collected in South Africa: 7,8-dihydroflabellatene A (1) and 7,8-dihydroflabellatene B (2) [2].
  • Sarcophytol A (SaA), a cembrane-type diterpene, inhibits pancreatic carcinogenesis induced by N-nitrosobis(2-oxypropyl)amine (BOP) in hamsters [3].

References

  1. Structure-related inhibiting activity of some tobacco cembranoids on the prostaglandin synthesis in vitro. Olsson, E., Holth, A., Kumlin, E., Bohlin, L., Wahlberg, I. Planta Med. (1993) [Pubmed]
  2. New cytotoxic cembranes from the sea pen Gyrophyllum sibogae. Reyes, F., Ardá, A., Martín, R., Fernández, R., Rueda, A., Montalvo, D., Gómez, C., Jiménez, C., Rodríguez, J., Sánchez-Puelles, J.M. J. Nat. Prod. (2004) [Pubmed]
  3. Inhibitory effect of sarcophytol A on pancreatic carcinogenesis after initiation by N-nitrosobis(2-oxypropyl)amine in Syrian hamsters. Yokomatsu, H., Hiura, A., Tsutsumi, M., Satake, K. Pancreas (1996) [Pubmed]
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