The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

GNF-PF-4337     2-phenyl-1H-quinolin-4-one

Synonyms: YT-1 Compound, CHEMBL277148, SureCN367268, AG-D-34677, SureCN1256551, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of NSC28866

  • Suppressive effect of 2-phenyl-4-quinolone (YT-1) on hind-paw edema and cutaneous vascular plasma extravasation in mice [1].
  • 2-Phenyl-4-quinolone and 9-oxo-9,10-dihydroacridine derivatives were synthesized and screened as potential antitumor promoters by examining the ability of the compounds to inhibit Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells [2].
 

High impact information on NSC28866

 

Anatomical context of NSC28866

References

  1. Suppressive effect of 2-phenyl-4-quinolone (YT-1) on hind-paw edema and cutaneous vascular plasma extravasation in mice. Wang, J.P., Hsu, M.F., Raung, S.L., Kuo, S.C. Naunyn Schmiedebergs Arch. Pharmacol. (1994) [Pubmed]
  2. Cancer preventive agents, Part 2: Synthesis and evaluation of 2-phenyl-4-quinolone and 9-oxo-9,10-dihydroacridine derivatives as novel antitumor promoters. Nakamura, S., Kozuka, M., Bastow, K.F., Tokuda, H., Nishino, H., Suzuki, M., Tatsuzaki, J., Morris Natschke, S.L., Kuo, S.C., Lee, K.H. Bioorg. Med. Chem. (2005) [Pubmed]
  3. Antitumor Agents. 211. Fluorinated 2-phenyl-4-quinolone derivatives as antimitotic antitumor agents. Xia, Y., Yang, Z.Y., Xia, P., Hackl, T., Hamel, E., Mauger, A., Wu, J.H., Lee, K.H. J. Med. Chem. (2001) [Pubmed]
  4. Involvement of cyclic AMP generation in the inhibition of respiratory burst by 2-phenyl-4-quinolone (YT-1) in rat neutrophils. Wang, J.P., Raung, S.L., Huang, L.J., Kuo, S.C. Biochem. Pharmacol. (1998) [Pubmed]
  5. 2-Phenyl-4-quinolone prevents serotonin-induced increases in endothelial permeability to albumin. Lee, H.Z., Lin, W.C., Yeh, F.T., Wu, C.H. Eur. J. Pharmacol. (1998) [Pubmed]
  6. Antitumor agents. Part 226: synthesis and cytotoxicity of 2-phenyl-4-quinolone acetic acids and their esters. Xia, Y., Yang, Z.Y., Xia, P., Bastow, K.F., Nakanishi, Y., Nampoothiri, P., Hamel, E., Brossi, A., Lee, K.H. Bioorg. Med. Chem. Lett. (2003) [Pubmed]
 
WikiGenes - Universities