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Chemical Compound Review: 

Sesbanimide     4-[5-hydroxy-6-(2-hydroxy-3- methyl-4...

Synonyms: SESBANIMIDE B, Sesbanimide A, AGN-PC-00G22Q, CHEMBL560362, NSC-355461, ...
 
 
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Disease relevance of K442

 

Analytical, diagnostic and therapeutic context of K442

  • 1. The HPLC separation of a water-soluble toxic fraction isolated from the seed of Sesbania vesicaria provided a potent antileukemic compound which was identified as sesbanimide (or sesbanimide A) [2].

References

  1. Two marine Agrobacterium producers of sesbanimide antibiotics. Acebal, C., Alcazar, R., Cañedo, L.M., de la Calle, F., Rodriguez, P., Romero, F., Fernandez Puentes, J.L. J. Antibiot. (1998) [Pubmed]
  2. Isolation of sesbanimide from the seed of Sesbania vesicaria. Kim, H.L., Krakoff, I.H., Newman, R.A. Gen. Pharmacol. (1992) [Pubmed]
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