Disease relevance of Lactosucrose

• Long-term ingestion of lactosucrose increases Bifidobacterium sp. in human fecal flora [1].
• These results suggest that lactosucrose may be useful for patients with chronic inflammatory bowel disease [2].
• After the administration of lactosucrose to two patients with Crohn's disease and five patients with ulcerative colitis for 2 weeks, significant induction of the growth of Bifidobacterium was observed, and significant reduction in the population level of Bacteroidaceae was seen [2].
• During lactosucrose administration, the counts of lactobacilli increased significantly (p < 0.05), whereas the counts of clostridia, including Clostridium perfringens and Enterobacteriaceace decreased significantly (p < 0.05) [3].
• Reaction kinetics and modeling of the enzyme-catalyzed production of lactosucrose using beta-fructofuranosidase from Arthrobacter sp. K-1 [4].

Psychiatry related information on Lactosucrose

• Under these conditions, the whole cells produced approximately 17.0% (w/v) lactosucrose in 6 h of reaction time with a productivity of 2.8% (w/v)/h [5].

High impact information on Lactosucrose

• The hydrolysis kinetics of trisaccharides consisting of glucose, galactose, and fructose residues with different glycosidic bonds, 1-kestose, d-melezitose, d-raffinose, and lactosucrose, in subcritical water were conducted over the temperature range of 150-230 degrees C and at a constant pressure of 10 MPa [6].
• (2) Using the pooled data of the total of 26 subjects, there was no significant seasonal variation in the orocecal transit time of the breakfast or the lactosucrose solution [7].
• Intestinal contents of rainbow trout reared at 15 degrees C were incubated with glucose, lactosucrose, sodium alginate or colloidal chitin (each 10 g/l) at 15 degrees C or 25 degrees C for 12 h [8].
• The apparent calcium-45 ((45)Ca) absorption, residual (45)Ca ratio in the body, and (45)Ca accumulation in the femur and tibia of lactosucrose-supplemented rats were significantly higher than in control rats 24 h after the administration of a (45)CaCl(2) solution [9].
• The levels of fusobacteria and staphylococci were decreased significantly (p < 0.01) on day 7 of lactosucrose administration, while the counts of bacteroides increased significantly (p < 0.05) and day 14 of lactosucrose administration compared to pre-administration [3].

Anatomical context of Lactosucrose

• The water content and weight of the feces increased slightly during lactosucrose administration, but the pH values decreased slightly [3].

Gene context of Lactosucrose

• In frequency of occurrence, bifidobacteria increased significantly (p < 0.001) during lactosucrose administration, while Spirochaetaceae and lecithinase-negative clostridia decreased significantly (p < 0.05) on day 14 of lactosucrose administration compared to pre-administration [3].

References