Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AC1L432C 2,3,6-trichloro-4-(3,4- dichlorophenyl)phenol

Synonyms: C14381, 152969-11-4, 2,3,3',4',5-pentachlorobiphenyl-4-ol, 2,3,3',4',5-Pentachloro-4-biphenylol, 4-Hydroxy-2,3,3',4',5-pentachlorobiphenyl, ...

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High impact information on 2,3,3',4',5-Pentachloro-4-biphenylol

Effects of in utero exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107) on developmental landmarks, steroid hormone levels, and female estrous cyclicity in rats [1].
Developmental exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107): long-term effects on brain development, behavior, and brain stem auditory evoked potentials in rats [2].
Tissue distribution and half-lives of individual polychlorinated biphenyls and serum levels of 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl in the rat [3].
On Day 90 postpartum, plasma levels of PCBs and 2,3,3',4',5-pentachloro-4-biphenylol were still elevated in the offspring of PCB-treated dams relative to controls [4].
An accumulation of mainly one PCB metabolite, 2,3,3',4',5-pentachloro-4-biphenylol was observed in fetal plasma and forebrain on Gestation Day 20 and in neonatal and weanling rat plasma on Postnatal Days 4, 21, and 90 [4].

References

Effects of in utero exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107) on developmental landmarks, steroid hormone levels, and female estrous cyclicity in rats. Meerts, I.A., Hoving, S., van den Berg, J.H., Weijers, B.M., Swarts, H.J., van der Beek, E.M., Bergman, A., Koeman, J.H., Brouwer, A. Toxicol. Sci. (2004) [Pubmed]
Developmental exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107): long-term effects on brain development, behavior, and brain stem auditory evoked potentials in rats. Meerts, I.A., Lilienthal, H., Hoving, S., van den Berg, J.H., Weijers, B.M., Bergman, A., Koeman, J.H., Brouwer, A. Toxicol. Sci. (2004) [Pubmed]
Tissue distribution and half-lives of individual polychlorinated biphenyls and serum levels of 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl in the rat. Oberg, M., Sjödin, A., Casabona, H., Nordgren, I., Klasson-Wehler, E., Håkansson, H. Toxicol. Sci. (2002) [Pubmed]
Alterations in rat brain thyroid hormone status following pre- and postnatal exposure to polychlorinated biphenyls (Aroclor 1254). Morse, D.C., Wehler, E.K., Wesseling, W., Koeman, J.H., Brouwer, A. Toxicol. Appl. Pharmacol. (1996) [Pubmed]

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