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Chemical Compound Review:

Pattonex 3-(4-bromophenyl)-1-methoxy- 1-methyl-urea

Synonyms: Patoran, Metbromuron, METOBROMURON, Monobromuron, Metobromurone, ...

Turcant, A. et al., Bonnemoy, F. et al., Balinova, A., Yang, C.C. et al.

Bonnemoy, Lavédrine, Boulkamh,

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Disease relevance of Metobromurone

The sharp initial increase of toxicity shown by metobromuron solutions is mainly due to intermediate photoproducts which rapidly disappear [1].
Acute metobromuron poisoning with severe associated methemoglobinemia. Identification of four metabolites in plasma and urine by LC-DAD, LC-ESI-MS, and LC-ESI-MS-MS [2].

High impact information on Metobromurone

Bentazone, 2,4-D, MCPA, fluazifop-acid, metoxuron, monolinuron, metobromuron, diuron, linuron, atrazine and simazine were determined simultaneously in a single run on a C18 HPLC column [3].
A 22-year-old woman at 36 weeks of gestation was admitted to the emergency department three hours after ingestion of a mixture of 25% metobromuron and 25% metolachlor [4].

Analytical, diagnostic and therapeutic context of Metobromurone

Metobromuron was analyzed by liquid chromatography with diode-array detection [2].

References

Influence of UV irradiation on the toxicity of phenylurea herbicides using Microtox test. Bonnemoy, F., Lavédrine, B., Boulkamh, A. Chemosphere (2004) [Pubmed]
Acute metobromuron poisoning with severe associated methemoglobinemia. Identification of four metabolites in plasma and urine by LC-DAD, LC-ESI-MS, and LC-ESI-MS-MS. Turcant, A., Cailleux, A., Le Bouil, A., Allain, P., Harry, P., Renault, A. Journal of analytical toxicology. (2000) [Pubmed]
Solid-phase extraction followed by high-performance liquid chromatographic analysis for monitoring herbicides in drinking water. Balinova, A. J. Chromatogr. (1993) [Pubmed]
Metobromuron/metolachlor ingestion with late onset methemoglobinemia in a pregnant woman successfully treated with methylene blue. Yang, C.C., Hwang, S.F., Chou, M.M., Deng, J.F. J. Toxicol. Clin. Toxicol. (1995) [Pubmed]

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