Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AG-K-71006 (2R,4S,5R)-2,4,5- trihydroxyhexanal

Synonyms: CHEBI:32478, CTK5A5373, AR-1E9985, AC1L4W7K, AC1Q6A7Y, ...

Svenungsson, B. et al., Wyk, P. et al.

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Disease relevance of Paratose

The O antigen of Salmonella group B strains contains the sugar abequose, whereas those from group A and D strains contain paratose or tyvelose in its place [1].

High impact information on Paratose

Antisera from rabbits immunized with the synthetic disaccharide paratose 1 leads to alpha 3 mannose, representive of Salmonella O-antigen 2, covalently linked to bovine serum albumin (BSA), were used in indirect immunofluorescence studies for the identification of Salmonella serogroup A (O-antigen 1,2,12) bacteria [2].

References

Identification and sequence of the gene for abequose synthase, which confers antigenic specificity on group B salmonellae: homology with galactose epimerase. Wyk, P., Reeves, P. J. Bacteriol. (1989) [Pubmed]
Synthetic disaccharide-protein antigen for production of specific O2 antiserum for immunofluorescence diagnosis of salmonella. Svenungsson, B., Linberg, A.A. Acta pathologica et microbiologica Scandinavica. Section B, Microbiology. (1978) [Pubmed]

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