Chemical Compound Review:
CHEMBL1288 naphthalen-1-ylmethanol
Synonyms:
PubChem18751, SureCN28403, NSC-5315, ACMC-1AKCI, AG-F-62641, ...
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High impact information on alpha-Naphthylmethanol
- The Kis for 1-naphthylacetic acid and 2-naphthylacetic acid as inhibitors of AST IV-catalyzed sulfation of 1-naphthalenemethanol were approximately 10-fold higher than those of the corresponding naphthoic acids [1].
Gene context of alpha-Naphthylmethanol
- Although none of the carboxylic acids tested were substrates for AST IV, they did competitively inhibit the enzyme with 1-naphthalenemethanol as substrate at pH 7 [1].
References
- Inhibition of aryl sulfotransferase by carboxylic acids. Rao, S.I., Duffel, M.W. Drug Metab. Dispos. (1991) [Pubmed]
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