Disease relevance of G 13529

• Exposure to terbuthylazine also affected the renal tubular epithelial cells, which exhibited 'blebs'. Damage to the intestinal epithelial cells was also observed [1].

Psychiatry related information on G 13529

• Signal response time was 1-3 min, and sensitivity of measurements in tap water was below 1 microgram l-1 of atrazine and terbutylazine [2].

High impact information on G 13529

• The application of liquid chromatography time-of-flight mass spectrometry (LC/TOF-MS) for the identification and quantitation of four herbicides (simazine, atrazine, diuron, and terbuthylazine) in olive oil samples is reported here [3].
• A number of contaminants was detected and quantified throughout the North Sea, among them the pesticides dichlobenil (2,6-dichlorobenzonitrile), metolachlor and terbuthylazine as well as the industrial chemicals dichloropyridines (DCPy, 4 isomers) and nitrobenzene [4].
• For terbuthylazine, fluorescence measurements showed an effect on photosynthesis within 1h of exposure, and reached a minimum after 3 h [5].
• In contrast to terbuthylazine, the stop in area-specific growth observed for the ALS-and microtubule assembly inhibitors, took up to 4 days to recover from [5].
• The herbicide terbuthylazine (CBET) has replaced atrazine in Italy and in many other countries because the use of the latter has been banned because of its adverse environmental impacts [6].

Biological context of G 13529

• Concentrations of terbuthylazine transformation products derived from dealkylation and hydroxylation reactions were measured in leachates and soil samples collected during the three experiments [7].
• The performance of a narrow buffer strip in abating dissolved P, electrical conductivity and herbicides (terbuthylazine, alachlor, nicosulfuron, pendimethalin, linuron) in subsurface water coming from cropland was tested in an experiment carried out on the low plains of the Veneto Region (NE Italy) [8].

Anatomical context of G 13529

• After screening with a competitive enzyme immunoassay, a monoclonal antibody that was specific for terbuthylazine and was produced by a permanent hybridoma cell line was selected for immunoassay development and optimization [9].

Associations of G 13529 with other chemical compounds

• Total herbicide loss with runoff was low (0.69-3.98 g ha(-1) without VFS, less than 0.27 g ha(-1) with VFS), but concentrations were sometimes very high, especially of terbuthylazine and isoproturon during the first events after treatment [10].
• Volatilization rates of pesticides (14C-labeled parathion-methyl, fenpropimorph, and terbuthylazine and nonlabeled chlorpyrifos) were determined in a wind-tunnel experiment after simultaneous soil surface application on Gleyic Cambisol [11].
• A field tracer test performed under natural flow conditions at the Twin Lake test site, Chalk River Laboratories of the Atomic Energy of Canada Ltd. in Chalk River, Ontario, Canada, using tritium and three herbicides (Chlortoluron, Terbuthylazine, and Pendimethalin) was interpreted using the dispersion equation with a combined reaction model [12].

Analytical, diagnostic and therapeutic context of G 13529

• Two different immunoassay (IA) formats for terbuthylazine analysis were developed and optimized using the same monoclonal antibodies [13].
• Optimization of a monoclonal antibody-based enzyme immunoassay for the detection of terbuthylazine [9].
• From 24 soil samples collected in the Veneto area, Italy, 18 samples contained different amounts of terbuthylazine (but <1 microg/kg atrazine) as was analyzed by gas chromatography with mass selective detection [13].
• The effects of acute exposure to the herbicide terbuthylazine (3.55, 5.01 and 7.08mgl(-1)) on the cells of farmed European sea bass, Dicentrarchus labrax L., were investigated by means of light and electron microscopy [1].
• An indirect format enzyme-linked immuno-sorbent assay (ELISA) on graphite rods ( 0.8 mm x 20 mm) and, for comparison, on microtiter plates has been developed against terbuthylazine [14].

References