Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Pregnanolone 1-(3-hydroxy-10,13-dimethyl- 2,3,4,5,6,7,8...

Synonyms: AGN-PC-00HTKJ, SureCN6447469, P8129_SIGMA, NSC-97078, AC1Q5CCU, ...

Brinton, R.D. et al.

Brinton, Wang,

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High impact information on Allopregnanolone

Allopregnanolone-induced proliferation was isomer and steroid specific, in that the stereoisomer 3beta-hydroxy-5beta-pregnan-20-one and related steroids did not increase (3)H-thymidine uptake [1].

References

Preclinical analyses of the therapeutic potential of allopregnanolone to promote neurogenesis in vitro and in vivo in transgenic mouse model of Alzheimer's disease. Brinton, R.D., Wang, J.M. Current Alzheimer research. (2006) [Pubmed]

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