Chemical Compound Review:
AC1MHVGL [(2R)-1-[[4-[[(1S)-1- methoxycarbonyl-3...
Synonyms:
ZINC13796722
This record was replaced with 3012117.
- Inhibition of Ras and related G-proteins as a therapeutic strategy for blocking malignant glioma growth. Bredel, M., Pollack, I.F., Freund, J.M., Hamilton, A.D., Sebti, S.M. Neurosurgery (1998)
- Pitavastatin-induced thrombomodulin expression by endothelial cells acts via inhibition of small G proteins of the Rho family. Masamura, K., Oida, K., Kanehara, H., Suzuki, J., Horie, S., Ishii, H., Miyamori, I. Arterioscler. Thromb. Vasc. Biol. (2003)
- Thrombin-induced rapid geranylgeranylation of RhoA as an essential process for RhoA activation in endothelial cells. Ohkawara, H., Ishibashi, T., Sakamoto, T., Sugimoto, K., Nagata, K., Yokoyama, K., Sakamoto, N., Kamioka, M., Matsuoka, I., Fukuhara, S., Sugimoto, N., Takuwa, Y., Maruyama, Y. J. Biol. Chem. (2005)
- Disruption of oncogenic K-Ras4B processing and signaling by a potent geranylgeranyltransferase I inhibitor. Lerner, E.C., Qian, Y., Hamilton, A.D., Sebti, S.M. J. Biol. Chem. (1995)
- A Rho-signaling pathway mediates cortical granule translocation in the sea urchin oocyte. Covián-Nares, F., Martínez-Cadena, G., López-Godínez, J., Voronina, E., Wessel, G.M., García-Soto, J. Mech. Dev. (2004)
- Statins downregulate myeloperoxidase gene expression in macrophages. Kumar, A.P., Reynolds, W.F. Biochem. Biophys. Res. Commun. (2005)
- Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines. Lerner, E.C., Zhang, T.T., Knowles, D.B., Qian, Y., Hamilton, A.D., Sebti, S.M. Oncogene (1997)
- Pharmacological modulation of fatty acid desaturation and of cholesterol biosynthesis in THP-1 cells. Risé, P., Ghezzi, S., Levati, M.G., Mirtini, R., Colombo, C., Galli, C. Lipids (2003)
- Effects of statins on adhesion molecule expression in endothelial cells. Dimitrova, Y., Dunoyer-Geindre, S., Reber, G., Mach, F., Kruithof, E.K., de Moerloose, P. J. Thromb. Haemost. (2003)