Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Apabglu (2S)-2-[(4-acetamidophenyl) carbonylamino]p...

Synonyms: AC1MIVVI, SureCN5285628, 60474-41-1, p-Acetamidobenzoylglutamate, 4-Acetamidobenzoylglutamate, ...

Stanley, L.A. et al., Upton, A. et al., Higgins, J.R. et al.

Stanley, Copp, Pope, Rolls, Smelt, Perry, Sim,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on p-Acetamidobenzoylglutamate

The discovery that human NAT1 acts upon p-aminobenzoylgluatamate (p-ABG) to generate p-acetamidobenzoylglutamate (p-AABG), a major urinary metabolite of folic acid, suggests that human NAT1 may play a role in folic acid metabolism and hence in the normal development of the neural tube [1].
MAIN OUTCOME MEASURES: Urinary levels of p-acetamidobenzoylglutamate and p-aminobenzoylglutamate were measured by high pressure liquid chromatography [2].

Associations of p-Acetamidobenzoylglutamate with other chemical compounds

Placental arylamine N-acetyltransferase type 1: potential contributory source of urinary folate catabolite p-acetamidobenzoylglutamate during pregnancy [3].

References

Immunochemical detection of arylamine N-acetyltransferase during mouse embryonic development and in adult mouse brain. Stanley, L.A., Copp, A.J., Pope, J., Rolls, S., Smelt, V., Perry, V.H., Sim, E. Teratology (1998) [Pubmed]
The relationship between increased folate catabolism and the increased requirement for folate in pregnancy. Higgins, J.R., Quinlivan, E.P., McPartlin, J., Scott, J.M., Weir, D.G., Darling, M.R. BJOG : an international journal of obstetrics and gynaecology. (2000) [Pubmed]
Placental arylamine N-acetyltransferase type 1: potential contributory source of urinary folate catabolite p-acetamidobenzoylglutamate during pregnancy. Upton, A., Smelt, V., Mushtaq, A., Aplin, R., Johnson, N., Mardon, H., Sim, E. Biochim. Biophys. Acta (2000) [Pubmed]

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