The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

ETHANEDITHIOL     ethane-1,1-dithiol

Synonyms: AG-E-85306, CTK1A5492, FEMA No. 4111, AC1L1Q05, 26914-40-9, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of ETHANEDITHIOL

  • The heat resistance of wild-type spores of Bacillus subtilis or spores (termed alpha-beta-) lacking DNA protective alpha/beta-type small, acid-soluble spore proteins was not altered by anaerobiosis or high concentrations of the free radical scavenging agents ethanethiol and ethanedithiol [1].
 

High impact information on ETHANEDITHIOL

  • We therefore established a staining protocol using beta-mercaptoethanol as thiol binding site competitor resulting in a specific staining of tetracysteine-tagged reggie-1/flotillin-2 of adequate signal to noise ratio, so that the more toxic and inconvenient ethanedithiol could be avoided [2].
  • The furyl group of (2-furyl)-L-alanine-containing peptides obtained from Fmoc solid-phase synthesis is partially degraded to several by-products during the final TFA-mediated deprotection in the presence of cation scavengers such as ethanedithiol and propanedithiol [3].
 

Gene context of ETHANEDITHIOL

  • The probe is stable to TFA deprotection/cleavage mixtures containing ethanedithiol commonly used in Fmoc-SPPS [4].

References

  1. Heat killing of Bacillus subtilis spores in water is not due to oxidative damage. Setlow, B., Setlow, P. Appl. Environ. Microbiol. (1998) [Pubmed]
  2. Accumulation of FlAsH/Lumio Green in active mitochondria can be reversed by beta-mercaptoethanol for specific staining of tetracysteine-tagged proteins. Langhorst, M.F., Genisyuerek, S., Stuermer, C.A. Histochem. Cell Biol. (2006) [Pubmed]
  3. Stability and cleavage conditions of (2-furyl)-L-alanine-containing peptides. Schulz, A., Busmann, A., Klüver, E., Schnebel, M., Adermann, K. Protein Pept. Lett. (2004) [Pubmed]
  4. Photochemical conjugation of peptides to carrier proteins using 1,2,3-thiadiazole-4-carboxylic acid. Immunoreactivity of free C-terminal epitope with specific antibodies. Hansen, P.R., Flyge, H., Holm, A., Lauritzen, E., Larsen, B.D. Int. J. Pept. Protein Res. (1996) [Pubmed]
 
WikiGenes - Universities