Chemical Compound Review:
PRBCM 2-(2-chloroethyl-propyl- amino)ethyl 2...
Synonyms:
PrBCh, AC1L1XMW, C12H15ClNO2, LS-174586, 36167-80-3, ...
- Blockade of cholinergic receptors by an irreversible antagonist, propylbenzilylcholine mustard (PrBCM), in the rat cerebral cortex causes deficits in passive avoidance learning. Fukuchi, I., Kato, S., Nakahiro, M., Uchida, S., Ishida, R., Yoshida, H. Brain Res. (1987)
- Experimental localization of muscarinic receptor subtypes to cingulate cortical afferents and neurons. Vogt, B.A., Burns, D.L. J. Neurosci. (1988)
- Muscarinic cholinergic receptor structure. Receptor size, membrane orientation, and absence of major phylogenetic structural diversity. Venter, J.C. J. Biol. Chem. (1983)
- Differential receptor occupancy requirements for muscarinic cholinergic stimulation of inositol lipid hydrolysis in brain and in neuroblastomas. Fisher, S.K., Snider, R.M. Mol. Pharmacol. (1987)
- Heterogeneity of binding sites on cardiac muscarinic receptors induced by the neuromuscular blocking agents gallamine and pancuronium. Dunlap, J., Brown, J.H. Mol. Pharmacol. (1983)
- Agarose gel keratinocyte outgrowth system as a model of skin re-epithelization: requirement of endogenous acetylcholine for outgrowth initiation. Grando, S.A., Crosby, A.M., Zelickson, B.D., Dahl, M.V. J. Invest. Dermatol. (1993)
- Mechanism of soman-induced contractions in canine tracheal smooth muscle. Adler, M., Moore, D.H., Filbert, M.G. Arch. Toxicol. (1992)
- Cardiac muscarinic receptors. Relationship between the G protein and multiple states of affinity. Green, M.A., Chidiac, P., Wells, J.W. Biochemistry (1997)
- Autoradiographic localization of functional muscarinic receptors in the rat superior cervical sympathetic ganglion reveals an extensive distribution over non-synaptic surfaces of neuronal somata, dendrites and nerve endings. Ramcharan, E.J., Matthews, M.R. Neuroscience (1996)
- Routes of delivery of muscarinic acetylcholine receptors to the plasma membrane in NG108-15 cells. Koenig, J.A., Edwardson, J.M. Br. J. Pharmacol. (1994)
- Effects of propylbenzilylcholine mustard on injection into the liquor space of cats. Bergmann, F., Feldberg, W. Br. J. Pharmacol. (1978)
- Muscarinic cholinergic receptor binding sites differentiated by their affinity for pirenzepine do not interconvert. Gil, D.W., Wolfe, B.B. J. Pharmacol. Exp. Ther. (1986)
- Distance between the propylbenzilylcholine mustard attachment site and carbohydrates and thiol groups in muscarinic acetylcholine receptor protein from rat cerebral cortex. Alperin, D.M., Bouzat, C.B., Barrantes, F.J. Biochem. J. (1988)
- Contrasting effects of carbachol, McN-A-343 and AHR-602 on Ca(2+)-mobilization and Ca(2+)-influx pathways in taenia caeci. Hishinuma, S., Hongo, I., Matsumoto, Y., Narita, F., Kurokawa, M. Br. J. Pharmacol. (1997)
- Guanosine 5'-triphosphate converts some populations of propylbenzilylcholine mustard-sensitive muscarinic cholinoceptor sites to sites resistant to the drug in intestinal smooth muscle. Kiuchi, Y., Kumagai, N., Hisayama, T., Takayanagi, I. Jpn. J. Pharmacol. (1991)
- Modification of cholinergic-mediated cellular transmembrane signals by the interaction of human chagasic IgG with cardiac muscarinic receptors. Goin, J.C., Perez Leiros, C., Borda, E., Sterin-Borda, L. Neuroimmunomodulation (1994)
- Irreversible and quaternary muscarinic antagonists discriminate multiple muscarinic receptor binding sites in rat brain. Norman, A.B., Eubanks, J.H., Creese, I. J. Pharmacol. Exp. Ther. (1989)
- Propylbenzilylcholine mustard has greater specificity for muscarinic m2 receptors than for m3 receptors present in cerebellar granule cell culture from rat. McLeskey, S.W., Wojcik, W.J. J. Pharmacol. Exp. Ther. (1992)
- Differential effects of alkylating agents on the multiple muscarinic receptor subtypes linked to activation of phospholipase C by carbachol in rat brain cortical membranes. Sallés, J., Wallace, M.A., Fain, J.N. J. Pharmacol. Exp. Ther. (1993)
- Afferent connections of anterior thalamus in rats: sources and association with muscarinic acetylcholine receptors. Sikes, R.W., Vogt, B.A. J. Comp. Neurol. (1987)