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Chemical Compound Review:

OCDF 1,2,3,4,6,7,8,9- octachlorodibenzofuran

Synonyms: PCDF 135, AG-F-37711, AC1L1ZAK, LS-61077, CTK4I0808, ...

Berends, A.G. et al., Buser, H.R., Kumagai, S. et al., Chen, C.Y. et al., Sinkkonen, S. et al., et al.

Sinkkonen, Paasivirta,

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Disease relevance of Octapolychlorinated dibenzofuran

Previous studies with octachlorodibenzo-p-dioxin (OCDD) and octachlorodibenzofuran (OCDF) in juvenile or adult fish exposed via water revealed no toxicity, despite significant bioaccumulation [1].

High impact information on Octapolychlorinated dibenzofuran

A dose-dependent increase in hepatic sequestration was seen with TCDD, PeCDD, 4-PeCDF, OCDF, PCB 126, and PCB 169, and the transfer to offspring was reduced at higher doses [2].
Multivariate analysis suggested that the serum concentration of HpCDF increased with duration of employment at the incineration plants and OCDF increased with employment of > or = 21 years [3].
Contents of three hexa- and two heptachlorodibenzofurans and octachlorodibenzofuran increased slightly from 1987 to 1994, but then at very high rate from 1994 to 1998 [4].
Bioaccumulation and lack of toxicity of octachlorodibenzofuran (OCDF) and octachlorodibenzo-p-dioxin (OCDD) to early-life stages of zebra fish (Brachydanio rerio) [1].
Octachlorodibenzofuran (OCDF) is the congener that most strongly correlates with occupational exposure in the magnesium plant [5].

Analytical, diagnostic and therapeutic context of Octapolychlorinated dibenzofuran

High-resolution gas chromatography using an OV-17 glass capillary column and mass spectrometry were used to analyze uv-and psi-irradiated octachlorodibenzo-rho-dioxin and octachlorodibenzofuran [6].

References

Bioaccumulation and lack of toxicity of octachlorodibenzofuran (OCDF) and octachlorodibenzo-p-dioxin (OCDD) to early-life stages of zebra fish (Brachydanio rerio). Berends, A.G., Boelhouwers, E.J., Thus, J.L., de Gerlache, J., de Rooij, C.G. Chemosphere (1997) [Pubmed]
Disposition of polychlorinated dibenzo-p-dioxins, dibenzofurans, and non-ortho polychlorinated biphenyls in pregnant long evans rats and the transfer to offspring. Chen, C.Y., Hamm, J.T., Hass, J.R., Birnbaum, L.S. Toxicol. Appl. Pharmacol. (2001) [Pubmed]
Polychlorinated dibenzo-p-dioxin and dibenzofuran concentrations in the serum samples of workers at continuously burning municipal waste incinerators in Japan. Kumagai, S., Koda, S., Miyakita, T., Yamaguchi, H., Katagi, K., Yasuda, N. Occupational and environmental medicine. (2000) [Pubmed]
Polychlorinated organic compounds in the Arctic cod liver: trends and profiles. Sinkkonen, S., Paasivirta, J. Chemosphere (2000) [Pubmed]
Occupational exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans in a magnesium production plant. Hansson, M., Grimstad, T., Rappe, C. Occupational and environmental medicine. (1995) [Pubmed]
Preparation of qualitative standard mixtures of polychlorinated dibenzo-rho-dioxins and dibenzofurans by ultraviolet and psi-irradiation of the octachloro compounds. Buser, H.R. J. Chromatogr. (1976) [Pubmed]

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