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Chemical Compound Review:

MIMP [(2R,3S,4R,5R)-3,4-dihydroxy- 5-(6-oxo-3H...

Synonyms: SureCN5787895, AC1L9RFZ, Methyl inosine monophosphate, Inosine 5'-methyl ester monophosphate

Naylor, P.H. et al., Mishin, V.P. et al., Hadden, E.M. et al., Masihi, K.N. et al., Hadden, J.W. et al.

Masihi, Hadden,

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Disease relevance of AIDS154387

Evaluation of methyl inosine monophosphate (MIMP) and peramivir activities in a murine model of lethal influenza A virus infection [1].
Methyl inosine monophosphate (MIMP), a new purine immunomodulator for HIV infection [2].
Protection by methyl inosine monophosphate (MIMP) against aerosol influenza virus infection in mice [3].

High impact information on AIDS154387

Methyl inosine monophosphate (MIMP) augments T-lymphocyte mitogen responses and reverses various immunosuppressants [4].
Also discussed is the possibility that thymomimetic agents such as thymosin alpha1, levamisole and methyl inosine monophosphate (MIMP) may be useful in enhancing the T cell mediated arm of the immune response [5].

References

Evaluation of methyl inosine monophosphate (MIMP) and peramivir activities in a murine model of lethal influenza A virus infection. Mishin, V.P., Hayden, F.G., Signorelli, K.L., Gubareva, L.V. Antiviral Res. (2006) [Pubmed]
Methyl inosine monophosphate (MIMP), a new purine immunomodulator for HIV infection. Hadden, J.W., Giner-Sorolla, A., Hadden, E.M. Int. J. Immunopharmacol. (1991) [Pubmed]
Protection by methyl inosine monophosphate (MIMP) against aerosol influenza virus infection in mice. Masihi, K.N., Hadden, J.W. Int. Immunopharmacol. (2002) [Pubmed]
Methyl inosine monophosphate (MIMP) augments T-lymphocyte mitogen responses and reverses various immunosuppressants. Hadden, E.M., Wang, Y., Sosa, M., Coffey, R.G., Giner-Sorolla, A., Hadden, J.W. Int. J. Immunopharmacol. (1995) [Pubmed]
T cell targeted immune enhancement yields effective T cell adjuvants. Naylor, P.H., Hadden, J.W. Int. Immunopharmacol. (2003) [Pubmed]

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