Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Prifinum 3-benzhydrylidene-1,1- diethyl-2-methyl-4,5...

Synonyms: Prifinium, AG-D-11251, SureCN14672576, AC1Q1ITK, CTK4A0968, ...

Sasaki, T. et al., Lacroix, D. et al.

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Disease relevance of Prifinum

When prifinium was added, a further but non-significant decrease of respiratory arrhythmia was observed, while the mean RR interval decreased from 1072 to 714 ms (P less than 0.01) [1].
Prifinium bromide's efficacy in the treatment of abnormal bowel movements was most evident in patients with diarrhea and slightly less evident in patients with alternation of diarrhea and constipation, and in constipated patients [2].

References

Effects of consecutive administration of central and peripheral anticholinergic agents on respiratory sinus arrhythmia in normal subjects. Lacroix, D., Logier, R., Kacet, S., Hazard, J.R., Dagano, J., Lekieffre, J. J. Auton. Nerv. Syst. (1992) [Pubmed]
Results of prifinium bromide therapy in irritable bowel syndrome. Sasaki, T., Takekoshi, T., Okada, T. Clinical therapeutics. (1985) [Pubmed]

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