Chemical Compound Review:
Perazolin [4-[2-[4-(2- methylpropoxycarbonyloxymethyl ...
Synonyms:
Sobuzoxano, sobuzoxane, Sobuzoxanum, MST-16, Lopac-S-4692, ...
- Phase II study: treatment of non-Hodgkin's lymphoma with an oral antitumor derivative of bis(2,6-dioxopiperazine). Ohno, R., Yamada, K., Hirano, M., Shirakawa, S., Tanaka, M., Oguri, T., Kodera, Y., Mitomo, Y., Ikeda, Y., Yokomaku, S. J. Natl. Cancer Inst. (1992)
- MST-16, a novel bis-dioxopiperazine anticancer agent, ameliorates doxorubicin-induced acute toxicity while maintaining antitumor efficacy. Yoshida, M., Maehara, Y., Sugimachi, K. Clin. Cancer Res. (1999)
- Arrest in late G2 or prophase of cell cycle induced by 4,4-(1,2-ethanediyl) bis (1-isobutoxycarbonyloxymethyl 2, 6-piperazinedione) (MST-16) in cultured L1210 cells. Liu, Y.P., Araya, S., Nakamura, T. Int. J. Cancer (1992)
- Effective treatment of adult T cell leukemia/lymphoma with a novel oral antitumor agent, MST-16. Ichihashi, T., Kiyoi, H., Fukutani, H., Kubo, K., Yamauchi, T., Naoe, T., Yamada, K., Ohno, R. Oncology (1992)
- Testicular degeneration induced in rat offspring by maternal treatment with sobuzoxane. Kato, I., Nobuhara, A., Wakasugi, N. Reprod. Toxicol. (1996)
- Xenoreactive CD4+ T cells and acute rejection of orthotopic guinea pig corneas in mice. Tanaka, K., Yamada, J., Streilein, J.W. Invest. Ophthalmol. Vis. Sci. (2000)
- Anti-proliferative effects, cell cycle G2/M phase arrest and blocking of chromosome segregation by probimane and MST-16 in human tumor cell lines. Lu, d.a. .Y., Huang, M., Xu, C.H., Yang, W.Y., Hu, C.X., Lin, L.P., Tong, L.J., Li, M.H., Lu, W., Zhang, X.W., Ding, J. BMC Pharmacol. (2005)
- Antitumor activities and schedule dependence of orally administered MST-16, a novel derivative of bis(2,6-dioxopiperazine). Narita, T., Koide, Y., Yaguchi, S., Kimura, S., Izumisawa, Y., Takase, M., Inaba, M., Tsukagoshi, S. Cancer Chemother. Pharmacol. (1991)
- Dioxopiperazine derivative potentiates antitumor effect of methylglyoxal bis(cyclopentylamidinohydrazone) on human and mouse leukemia cells. Hibasami, H., Tsukada, T., Shirakawa, S., Narita, T., Inagaki, M., Nakashima, K. Anticancer Res. (1994)
- Medicinal chemistry of probimane and MST-16: comparison of anticancer effects between bisdioxopiperazines. Lu, D.Y., Huang, M., Xu, C.H., Zhu, H., Xu, B., Ding, J. Medicinal chemistry (Sh⁻ariqah, United Arab Emirates) (2006)
- MST-16, a novel derivative of bis(2,6-dioxopiperazine), synergistically enhances the antitumor effects of anthracyclines. Inutsuka, S., Baba, H., Maehara, Y., Sugimachi, K. Cancer Chemother. Pharmacol. (1998)
- Secondary acute promyelocytic leukemia in a patient with non-Hodgkin's lymphoma treated with VP-16 and MST-16. Okamoto, T., Okada, M., Wakae, T., Mori, A., Takatsuka, H., Kakishita, E. Int. J. Hematol. (2002)
- Durable remission by sobuzoxane in an HIV-seronegative patient with human herpesvirus 8-negative primary effusion lymphoma. Inoue, Y., Tsukasaki, K., Nagai, K., Soda, H., Tomonaga, M. Int. J. Hematol. (2004)