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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chemical Compound Review: 

CHEMBL518414     [(2R,3S,4S,5R,6R)-6-[2-(3,4...

Synonyms: CHEBI:68345, CHEBI:603400, MEGxp0_000508, AC1NRV68, DNC008874, ...
 
 
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Disease relevance of AIDS-224552

  • Among the isolated compounds, calceolarioside B ( 2) and esculetin ( 7) showed moderate binding affinity on HIV gp41 with IC 50 values of 0.1 mg/ml and 0.5 mg/ml, respectively [1].
 

High impact information on AIDS-224552

  • We have isolated four different phenylethanoid glycosides (purpureaside A, desrhamnosyl acteoside, calceolarioside B and plantainoside D) from the leaves of Digitalis purpurea (foxglove) [2].

References

  1. HIV gp41 binding phenolic components from Fraxinus sieboldiana var. angustata. Kim, H.J., Yu, Y.G., Park, H., Lee, Y.S. Planta Med. (2002) [Pubmed]
  2. Effects of phenylethanoid glycosides from Digitalis purpurea L. on the expression of inducible nitric oxide synthase. Oh, J.W., Lee, J.Y., Han, S.H., Moon, Y.H., Kim, Y.G., Woo, E.R., Kang, K.W. J. Pharm. Pharmacol. (2005) [Pubmed]
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