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Chemical Compound Review: 

Pelubiprofen     2-[4-[(E)-(2- oxocyclohexylidene) methyl]phe...

Synonyms: AC1NQZNM, CHEMBL69308, SureCN188062, CS-670, RS-2131, ...
 
 
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Analytical, diagnostic and therapeutic context of Pelubiprofen

  • Stereoselective determination of the active metabolites of a new anti-inflammatory agent (CS-670) in human and rat plasma using antibody-mediated extraction and high-performance liquid chromatography [1].
  • Plasma concentrations and urinary excretion of CS-670 and its metabolites were determined in experimental subjects after oral administration at a single 120 mg dose [2].
  • Disposition of CS-670, a novel nonsteroidal anit-inflammatory drug, and its metabolites in healthy human volunteers [2].

References

  1. Stereoselective determination of the active metabolites of a new anti-inflammatory agent (CS-670) in human and rat plasma using antibody-mediated extraction and high-performance liquid chromatography. Takasaki, W., Asami, M., Muramatsu, S., Hayashi, R., Tanaka, Y., Kawabata, K., Hoshiyama, K. J. Chromatogr. (1993) [Pubmed]
  2. Disposition of CS-670, a novel nonsteroidal anit-inflammatory drug, and its metabolites in healthy human volunteers. Asami, M., Shigeta, A., Tanaka, Y. Chirality. (1996) [Pubmed]
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