Chemical Compound Review:
Taprostene 3-[(Z)-[(1R,5S,7R,8S)-8- [(E,3S)-3...
Synonyms:
Taprosteno, Taprostenum, AC1NSKAK, SureCN364129, CHEMBL2104890, ...
- Endothelium and myocardial protecting actions of taprostene, a stable prostacyclin analogue, after acute myocardial ischemia and reperfusion in cats. Johnson, G., Furlan, L.E., Aoki, N., Lefer, A.M. Circ. Res. (1990)
- The effect of taprostene in patients with acute myocardial infarction treated with thrombolytic therapy: results of the START study. Saruplase Taprostene Acute Reocclusion Trial. Bär, F.W., Meyer, J., Michels, R., Uebis, R., Lange, S., Barth, H., Groves, R., Vermeer, F. Eur. Heart J. (1993)
- Effects of taprostene, a chemically stable prostacyclin analogue, in patients with ischaemic peripheral vascular disease: a placebo controlled double-blind trial. Virgolini, I., Fitscha, P., O'Grady, J., Barth, H., Sinzinger, H. Prostaglandins Leukot. Essent. Fatty Acids (1989)
- Taprostene, a stable prostacyclin analogue, enhances the thrombolytic efficacy of saruplase (recombinant single-chain urokinase-type plasminogen activator) in rabbits with pulmonary embolized thrombi. Schneider, J. Prostaglandins (1991)
- Vascular endothelial growth factor/vascular permeability factor enhances vascular permeability via nitric oxide and prostacyclin. Murohara, T., Horowitz, J.R., Silver, M., Tsurumi, Y., Chen, D., Sullivan, A., Isner, J.M. Circulation (1998)
- The mechanisms of enhancement and inhibition of field stimulation responses of guinea-pig vas deferens by prostacyclin analogues. Tam, F.S., Chan, K., Borreau, J.P., Jones, R.L. Br. J. Pharmacol. (1997)
- Beneficial effects of the prostacyclin analogue taprostene on cardiovascular, pulmonary and renal disturbances in endotoxin-shocked rabbits. Schneider, J. Eicosanoids (1991)
- In vivo studies with the stabilized epoprostenol analogue taprostene. Effects on platelet functions and blood clotting. Michel, G., Seipp, U. Arzneimittel-Forschung. (1990)
- Partial agonism of taprostene at prostanoid IP receptors in vascular preparations from guinea-pig, rat, and mouse. Chan, K.M., Jones, R.L. J. Cardiovasc. Pharmacol. (2004)
- Effects of taprostene on neutrophil-endothelial interactions in isolated coronary arteries. Lefer, A.M., Murohara, T., Buerke, M. Methods and findings in experimental and clinical pharmacology. (1994)
- Neutrophil count and amputation in critical limb ischaemia. Belch, J.J., Söhngen, M., Robb, R., Voleske, P., Söhngen, W. International angiology : a journal of the International Union of Angiology. (1999)
- Effects of prostacyclin and taprostene in splanchnic artery occlusion shock. VanAntwerp, D.R., Hedley, L.R., Spires, D.A., Strosberg, A.M., Johnson, G., Lefer, A.M. Eicosanoids (1991)
- Effects of prostacyclin on hearing recovery after repetitive noise and on histomorphology of the inner ear in the guinea pig. Michel, O., Walger, M., Schrott-Fischer, A. ORL J. Otorhinolaryngol. Relat. Spec. (1994)
- Effects of taprostene, a stable prostacyclin analogue, on haemodynamics, platelet function and arachidonate metabolism in healthy volunteers. Virgolini, I., Fitscha, P., Sinzinger, H., Barth, H. Eur. J. Clin. Pharmacol. (1990)
- In vitro studies with the stabilized epoprostenol analogue taprostene. Effect on platelets and erythrocytes. Michel, G., Seipp, U. Arzneimittel-Forschung. (1990)
- Pilot study of the effects of taprostene (CG 4203) in patients with advanced peripheral arterial disease. Darius, H., Kopp, H., Mulfinger, A., Spielberger, M., Todt, M., Schuster, C.J., Meyer, J. Prog. Clin. Biol. Res. (1989)
- Agonists can discriminate between cloned human and mouse prostacyclin receptors. Chow, K.B., Jones, R.L., Wise, H. Prostaglandins Leukot. Essent. Fatty Acids (2004)
- In vitro analysis of synergistic effects of fibrinolytic agents and prostacyclin analogues. Spiecker, M., Heinke, B., Meyer, J., Darius, H. Haemostasis (1997)
- Additional myocardial salvage by coadministration of the epoprostenol analog taprostene to recombinant single-chain urokinase-type plasminogen activator in a canine coronary thrombosis model. Groves, R., Schneider, J., Friderichs, E., Giertz, H., Flohé, L. Arzneimittel-Forschung. (1989)