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Chemical Compound Review

AC1NSMRG     octadec-17-enoic acid

Synonyms: LMFA01030293, A834979, 17-octadecenoic acid
 
 
 
 
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Disease relevance of octadec-17-enoic acid

  • To determine whether a reduction in 20-HETE production in the outer medulla is sufficient to induce hypertension, an inhibitor of the renal metabolism of arachidonic acid by P450 enzymes, 17-octadecenoic acid (17-ODYA), was chronically infused directly into the outer medulla of the left kidney of uninephrectomized Lewis rats fed a high salt diet [1].

References

  1. Inhibition of renal outer medullary 20-HETE production produces hypertension in Lewis rats. Stec, D.E., Mattson, D.L., Roman, R.J. Hypertension (1997) [Pubmed]
 
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