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Chemical Compound Review:

Morroniside methyl(2R,4R)-4-hydroxy-2- methyl-10-[(2S...

Synonyms:

Xu, H.Q. et al., Wang, S.F. et al.

Xu, Hao, Zhang, Pan,

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High impact information on Morroniside

An efficient micellar electrokinetic capillary chromatography method was developed to analyze three major active components including morroniside, loganin and gallic acid in Fructus corni and its six preparations for the first time [1].
AIM: To determine whether morroniside, a compound in Cornus officinalis Sieb et Zucc can prevent cultured human umbilical vein endothelial cells (HUVEC) from damage by high ambient glucose [2].
With the intervention of morroniside (final concentration 100 and 10 micromol/L), the cell survival was significantly recovered (P<0.01, P<0.05, respectively), accompanied with increased S-phase rate and less extent of morphological damage [2].

References

Analysis of three effective components in Fructus corni and its preparations by micellar electrokinetic capillary chromatography. Wang, S.F., Chen, X.G., Hu, Z.D., Ju, Y. Biomed. Chromatogr. (2003) [Pubmed]
Morroniside protects cultured human umbilical vein endothelial cells from damage by high ambient glucose. Xu, H.Q., Hao, H.P., Zhang, X., Pan, Y. Acta Pharmacol. Sin. (2004) [Pubmed]

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