Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Atractylodin 2-[(1E,7E)-nona-1,7-dien-3,5- diynyl]furan

Synonyms: AKOS006281381, FT-0688290, AC1NT04U, O921, C16918, ...

Takeda, O. et al., Hiraoka, N., Kohjyouma, M. et al., Nakai, Y. et al.

Nakai, Kido, Hashimoto, Kase, Sakakibara, Higuchi, Sasaki,

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High impact information on Atractylodin

After two or three years' cultivation, main essential oil components, i.e., the sesquiterpenes: elemol ( 1), atractylon ( 2), hinesol ( 3), beta -eudesmol ( 4), selina-4(14),7(11)-dien-8-one ( 5), and the polyacetylene of atractylodin ( 6) were determined by capillary gas chromatography [1].
In addition, atractylodin improved the delay in gastric emptying at between 0.1 and 0.3 mg/kg in a dose-dependent manner [2].
One of the selected tetraploid lines had about 1.5 times as heavy rhizomes as the diploid and contained atractylodin, hinesol and beta-eudesmol in the rhizome to as great an extent or slightly less than the diploids [3].
Furthermore, quantitative analysis of atractylon, hinesol, beta-eudesmol and atractylodin in the rhizomes was done using gas chromatography [4].

References

A Comparative Study on Essential Oil Components of Wild and Cultivated Atractylodes lancea and A. chinensis. Takeda, O., Miki, E., Terabayashi, S., Okada, M., Lu, Y., He, H.S., He, S.A. Planta Med. (1996) [Pubmed]
Effect of the rhizomes of Atractylodes lancea and its constituents on the delay of gastric emptying. Nakai, Y., Kido, T., Hashimoto, K., Kase, Y., Sakakibara, I., Higuchi, M., Sasaki, H. Journal of ethnopharmacology. (2003) [Pubmed]
Atractylodes lancea autotetraploids induced by colchicine treatment of shoot cultures. Hiraoka, N. Biol. Pharm. Bull. (1998) [Pubmed]
Random amplified polymorphic DNA analysis and variation of essential oil components of Atractylodes plants. Kohjyouma, M., Nakajima, S., Namera, A., Shimizu, R., Mizukami, H., Kohda, H. Biol. Pharm. Bull. (1997) [Pubmed]

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