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Chemical Compound Review

Karmesin     disodium (3Z)-4-oxo-3-[(4...

Synonyms: Nacarat, Carmoisine S, Carmoisine W, Chromotrope FB, Carmoisine ba, ...
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Disease relevance of Chromotrop FB

 

High impact information on Chromotrop FB

  • Cyanidin 3-rutinoside, a simple anthocyanin, (+)-catechin, a flavanol, and carmoisine, a synthetic food colorant, were found to be particularly potent, reversible inhibitors of PST P [5].
  • Staining of the prolactin cells with carmoisine was extensive [6].
  • The kinetics of the decolourisation and mineralisation of three different dyes solutions (CI Acid Blue 113, CI Reactive Red 241 and CI Basic Red 14) were studied in a laboratory scale reactor by three different processes: adsorption on activated carbon, oxidation with ozone and ozonation in the presence of activated carbon [7].
  • The toxicity of carmoisine and of its metabolites after interaction with media components, was studied using the single cell system of Tetrahymena pyriformis [8].
  • The results demonstrate that the pregnancy does not affect the kinetic and the metabolic profile of a single oral administration of the azodye Carmoisine given at different days of gestation [9].
 

Biological context of Chromotrop FB

 

Anatomical context of Chromotrop FB

 

Associations of Chromotrop FB with other chemical compounds

  • Herlant's erythrosin and Brookes' carmoisine methods, claimed spedifically to stain prolactin cells, failed to provide reliable results, hence their use cannot be recommended in tumour identification [14].
  • We report the case of an 8.5-year-old girl with oro-facial granulomatosis associated with clinical atopy, in whom relapse of her granulomatous disorder was shown to be related to exposure to specific food additives, viz. carmoisine, sunset yellow and monosodium glutamate [15].
 

Analytical, diagnostic and therapeutic context of Chromotrop FB

  • Analyses by HPLC, combined with a radioactivity monitor (RAM), of urine and faeces of such animals show that five radioactive peaks were present in the radiochromatogram in addition to unmodified Carmoisine [9].
  • Decolorization of dye solution containing Acid Red 14 by electrocoagulation with a comparative investigation of different electrode connections [16].

References

  1. Long-term toxicity study of carmoisine in rats using animals exposed in utero. Ford, G.P., Stevenson, B.I., Evans, J.G. Food Chem. Toxicol. (1987) [Pubmed]
  2. 'Acidophilic' pituitary tumors: a reappraisal with differential staining and immunocytochemical techniques. Halmi, N.S., Duello, T. Arch. Pathol. Lab. Med. (1976) [Pubmed]
  3. "Now you see it...now you don't." Carmoisine vital dye facilitates complete removal of cutaneous neoplasia by intraoperative visual enhancement. Murphy, K.D., Hall, P.N. British journal of plastic surgery. (2003) [Pubmed]
  4. Reduction rate of 14C-Carmoisine by resting cell bacterial suspension from human and rat faeces. Flaminio, L.M., Tragni, E., De Giorgi, A., Brusa, T., Galli, C.L. Pharmacological research communications. (1988) [Pubmed]
  5. In vitro inhibition of phenolsulphotransferase by food and drink constituents. Gibb, C., Glover, V., Sandler, M. Biochem. Pharmacol. (1987) [Pubmed]
  6. Prolactin and growth hormone cells in the human hypophysis: a study with immunoenzyme histochemistry and differential staining. Halmi, N.S., Parsons, J.A., Erlandsen, S.L., Duello, T. Cell Tissue Res. (1975) [Pubmed]
  7. Mineralisation of coloured aqueous solutions by ozonation in the presence of activated carbon. Faria, P.C., Orfão, J.J., Pereira, M.F. Water Res. (2005) [Pubmed]
  8. In vitro toxicity evaluation of a product obtained from carmoisine using Tetrahymena pyriformis cells. Marathe, S.A., Adhikari, H.R., Netrawali, M.S., Nair, P.M. Food Chem. Toxicol. (1993) [Pubmed]
  9. Similar profile of urinary and faecal metabolites of 14C-carmoisine in male and pregnant female rats after oral administration. Tragni, E., Flaminio, L.M., Galli, C.L., Marinovich, M. Journal of applied toxicology : JAT. (1985) [Pubmed]
  10. Multigeneration reproduction studies with carmoisine in rats. Holmes, P.A., Pritchard, A.B., Kirschman, J.C. Toxicology (1978) [Pubmed]
  11. Null cell adenoma of the human pituitary. Kovacs, K., Horvath, E., Ryan, N., Ezrin, C. Virchows Archiv. A, Pathological anatomy and histology. (1980) [Pubmed]
  12. Synthetic organic food colouring agents and their degraded products: effects on human and rat cholinesterases. Osman, M.Y., Sharaf, I.A., Osman, H.M., El-Khouly, Z.A., Ahmed, E.I. Br. J. Biomed. Sci. (2004) [Pubmed]
  13. Spontaneous pituitary adenomas in aging rats. A light microscopic, immunocytological and fine structural study. Kovacs, K., Horvath, E., Ilse, R.G., Ezrin, C., Ilse, D. Beiträge zur Pathologie. (1977) [Pubmed]
  14. Localization of prolactin in chromophobe pituitary adenomas: study of human necropsy material by immunoperoxidase technique. Kovacs, K., Corenblum, B., Sirek, A.M., Penz, G., Ezrin, C. J. Clin. Pathol. (1976) [Pubmed]
  15. Oro-facial granulomatosis. Response to elemental diet and provocation by food additives. Sweatman, M.C., Tasker, R., Warner, J.O., Ferguson, M.M., Mitchell, D.N. Clin. Allergy (1986) [Pubmed]
  16. Decolorization of dye solution containing Acid Red 14 by electrocoagulation with a comparative investigation of different electrode connections. Daneshvar, N., Sorkhabi, H.A., Kasiri, M.B. Journal of hazardous materials. (2004) [Pubmed]
 
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