Disease relevance of Oxanol VI

• A transport ATPase from Enterococcus hirae was reconstituted in lipid vesicles and its electrogenic action investigated with the fluorescent dye oxonol VI as membrane potential probe [1].

High impact information on Oxanol VI

• Use of the indicator Oxonol VI showed that V-H(+)-PPase activity generated a membrane potential [2].
• The proton gradient (delta pH) and electrical potential (delta psi) across the neurosecretory vesicles were measured using the optical probes 9-aminoacridine and Oxanol VI, respectively [3].
• Extraction of FB from submitochondrial particles results in a decrease in ATP-dependent proton translocation (delta pH) and binding of the voltage-sensitive dye, oxonol VI [4].
• Electrophysiological study with oxonol VI of passive NO3- transport by isolated plant root plasma membrane [5].
• Charge transfer during Ca2+ uptake by rabbit skeletal muscle sarcoplasmic reticulum vesicles as measured with oxanol VI [6].

Biological context of Oxanol VI

• Kinetics of the potential-sensitive extrinsic probe oxonol VI in beef heart submitochondrial particles [7].

Associations of Oxanol VI with other chemical compounds

• Mg2+ ATP caused a marked carbonyl cyanide p-trifluoromethoxyphenylhydrazone-sensitive change in the membrane potential measured using Oxanol VI (plus 100 mV inside positive), presumably due to H+ translocation across the neurosecretory vesicle membrane [3].
• Changes of the membrane potential were monitored using the dyes oxonol VI and 3,3'-diisopropylthiodicarbocyanine iodide, and changes of the H+ gradient were followed using acridine orange [8].
• The interaction of the dyes oxonol V and oxonol VI with unilamellar dioleoylphosphatidylcholine vesicles was investigated using a fluorescence stopped-flow technique [9].

Gene context of Oxanol VI

• Energy transduction in an ATPase complex (complex V) has been studied in two reactions catalyzed by this system, i.e., ATP-dependent spectral shift of oxonol VI, and ATP-Pi exchange activity [10].

Analytical, diagnostic and therapeutic context of Oxanol VI

• The influence of membrane potential upon the rate of crystallization was studied by ion substitution using oxonol VI and 3,3'-diethyl-2,2'-thiadicarbocyanine (Di-S-C2(5] to monitor inside positive or inside negative membrane potentials, respectively [11].

References