Chemical Compound Review:
PELDESINE 3-amino-9-(pyridin-3- ylmethyl)-2,4,7...
Synonyms:
BCX-34, SureCN61135, SureCN61136, CHEMBL311300, BCX 34, ...
- A phase III, randomized, double-blind, placebo-controlled study of peldesine (BCX-34) cream as topical therapy for cutaneous T-cell lymphoma. Duvic, M., Olsen, E.A., Omura, G.A., Maize, J.C., Vonderheid, E.C., Elmets, C.A., Shupack, J.L., Demierre, M.F., Kuzel, T.M., Sanders, D.Y. J. Am. Acad. Dermatol. (2001)
- Effects of a novel purine nucleoside phosphorylase inhibitor, BCX-34, on activation and proliferation of normal human lymphoid cells. Conry, R.M., Bantia, S., Turner, H.S., Barlow, D.L., Allen, K.O., LoBuglio, A.F., Montgomery, J.A., Walsh, G.M. Immunopharmacology (1998)
- In vivo and in vitro pharmacologic activity of the purine nucleoside phosphorylase inhibitor BCX-34: the role of GTP and dGTP. Bantia, S., Montgomery, J.A., Johnson, H.G., Walsh, G.M. Immunopharmacology (1996)
- Pharmacokinetics and pharmacodynamics of peldesine (BCX-34), a purine nucleoside phosphorylase inhibitor, following single and multiple oral doses in healthy volunteers. Viegas, T.X., Omura, G.A., Stoltz, R.R., Kisicki, J. Journal of clinical pharmacology. (2000)
- BCX-34: a novel T-cell selective immunosuppressant: purine nucleoside phosphorylase (PNP) inhibitor. Wada, Y., Yagihashi, A., Terasawa, K., Miyao, N., Hirata, K., Cicciarelli, J., Iwaki, Y. Artificial organs. (1996)
- Purine nucleoside phosphorylase inhibitor BCX-1777 (Immucillin-H)--a novel potent and orally active immunosuppressive agent. Bantia, S., Miller, P.J., Parker, C.D., Ananth, S.L., Horn, L.L., Kilpatrick, J.M., Morris, P.E., Hutchison, T.L., Montgomery, J.A., Sandhu, J.S. Int. Immunopharmacol. (2001)
- Inhibitors of the enzyme purine nucleoside phosphorylase as potential therapy for psoriasis. Morris, P.E., Omura, G.A. Curr. Pharm. Des. (2000)
- Preformulation studies for the development of a parenteral liquid formulation of the immunomodulator, peldesine. Viegas, T.X., Van Winkle, L.L. PDA journal of pharmaceutical science and technology / PDA. (1999)