Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Tiglylglycine 2-[[(E)-2-methylbut-2- enoyl]amino]ethanoic...

Synonyms: Tiglyl Glycine, CHEBI:73018, HMDB00959, AC1O5VJH, KB-58902, ...

Rosa, R.B. et al.

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High impact information on Tiglylglycine

Biochemically, beta-ketothiolase deficiency is characterized by intermittent ketoacidosis and urinary excretion of 2-methyl-acetoacetate (MAA), 2-methyl-3-hydroxybutyrate (MHB) and tiglylglycine (TG), whereas in MHBD deficiency only MHB and tiglylglycine accumulate [1].

References

Inhibition of energy metabolism by 2-methylacetoacetate and 2-methyl-3-hydroxybutyrate in cerebral cortex of developing rats. Rosa, R.B., Schuck, P.F., de Assis, D.R., Latini, A., Dalcin, K.B., Ribeiro, C.A., da C Ferreira, G., Maria, R.C., Leipnitz, G., Perry, M.L., Filho, C.S., Wyse, A.T., Wannmacher, C.M., Wajner, M. J. Inherit. Metab. Dis. (2005) [Pubmed]

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