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Chemical Compound Review

dihydroS1P     [(2S,3R)-2-amino-3-hydroxy...

Synonyms: CHEMBL78494, AG-L-65424, CHEBI:16893, HMDB01383, CBiol_001741, ...
 
 
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High impact information on Sphinganine-phosphate

  • Mass levels of S1P and DHS1P in multiple biological samples, including human plasma, mouse plasma, and mouse brain tissues (e.g., cortex, cerebellum, spinal cord, and brain stem), were determined by the developed methodology [1].
  • The addition of sphingosine (1 microM) to human pulmonary artery endothelial cells in culture resulted in a more than 20-fold increase in the cellular level of S1P, whereas the level of DHS1P was unchanged [2].
  • The levels of S1P and DHS1P in fetal bovine serum were 141.7+/-4.6 and 0.6+/-0.2 pmol/ml, respectively [2].

References

 
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