Chemical Compound Review:
CHEMBL2331803 but-2-enedioic acid; (2S)-1-(6-chloro-5...
Synonyms:
SureCN8959555, LS-183389, AC1O64DP, Ro 60-0175, 169675-09-6
- Studies to investigate the role of 5-HT(2C) receptors on cocaine- and food-maintained behavior. Grottick, A.J., Fletcher, P.J., Higgins, G.A. J. Pharmacol. Exp. Ther. (2000)
- The atypical 5-HT2 receptor mediating tachycardia in pithed rats: pharmacological correlation with the 5-HT2A receptor subtype. Centurión, D., Ortiz, M.I., Saxena, P.R., Villalón, C.M. Br. J. Pharmacol. (2002)
- Comparative effects of continuous infusion of mCPP, Ro 60-0175 and d-fenfluramine on food intake, water intake, body weight and locomotor activity in rats. Vickers, S.P., Benwell, K.R., Porter, R.H., Bickerdike, M.J., Kennett, G.A., Dourish, C.T. Br. J. Pharmacol. (2000)
- mCPP-induced hyperactivity in 5-HT2C receptor mutant mice is mediated by activation of multiple 5-HT receptor subtypes. Dalton, G.L., Lee, M.D., Kennett, G.A., Dourish, C.T., Clifton, P.G. Neuropharmacology (2004)
- Similarities in the action of Ro 60-0175, a 5-HT2C receptor agonist and d-fenfluramine on feeding patterns in the rat. Clifton, P.G., Lee, M.D., Dourish, C.T. Psychopharmacology (Berl.) (2000)
- Effects of RO 60 0175, a 5-HT(2C) receptor agonist, in three animal models of anxiety. Kennett, G., Lightowler, S., Trail, B., Bright, F., Bromidge, S. Eur. J. Pharmacol. (2000)
- The role of 5-HT2C receptors in affective disorders. Jenck, F., Bös, M., Wichmann, J., Stadler, H., Martin, J.R., Moreau, J.L. Expert opinion on investigational drugs. (1998)
- Neuroendocrine evidence that (S)-2-(chloro-5-fluoro-indol- l-yl)-1-methylethylamine fumarate (Ro 60-0175) is not a selective 5-hydroxytryptamine(2C) receptor agonist. Damjanoska, K.J., Muma, N.A., Zhang, Y., D'Souza, D.N., Garcia, F., Carrasco, G.A., Kindel, G.H., Haskins, K.A., Shankaran, M., Petersen, B.R., Van De Kar, L.D. J. Pharmacol. Exp. Ther. (2003)
- Agomelatine(S 20098) antagonizes the penile erections induced by the stimulation of 5-HT2C receptors in Wistar rats. Chagraoui, A., Protais, P., Filloux, T., Mocaër, E. Psychopharmacology (Berl.) (2003)
- Serotonin inhibition of the NMDA receptor/nitric oxide/cyclic GMP pathway in human neocortex slices: involvement of 5-HT(2C) and 5-HT(1A) receptors. Maura, G., Marcoli, M., Pepicelli, O., Rosu, C., Viola, C., Raiteri, M. Br. J. Pharmacol. (2000)
- Mirtazapine enhances frontocortical dopaminergic and corticolimbic adrenergic, but not serotonergic, transmission by blockade of alpha2-adrenergic and serotonin2C receptors: a comparison with citalopram. Millan, M.J., Gobert, A., Rivet, J.M., Adhumeau-Auclair, A., Cussac, D., Newman-Tancredi, A., Dekeyne, A., Nicolas, J.P., Lejeune, F. Eur. J. Neurosci. (2000)
- Serotonin 2C receptor agonists and the behavioural satiety sequence in mice. Hewitt, K.N., Lee, M.D., Dourish, C.T., Clifton, P.G. Pharmacol. Biochem. Behav. (2002)
- Thermogenic effect of YM348, a novel 5-HT2C-receptor agonist, in rats. Hayashi, A., Suzuki, M., Sasamata, M., Miyata, K. J. Pharm. Pharmacol. (2004)
- SB 242084, a selective serotonin2C receptor antagonist, increases dopaminergic transmission in the mesolimbic system. Di Matteo, V., Di Giovanni, G., Di Mascio, M., Esposito, E. Neuropharmacology (1999)
- Biochemical and electrophysiological evidence that RO 60-0175 inhibits mesolimbic dopaminergic function through serotonin(2C) receptors. Di Matteo, V., Di Giovanni, G., Di Mascio, M., Esposito, E. Brain Res. (2000)
- 8-OH-DPAT-induced spontaneous tail-flicks in the rat are facilitated by the selective serotonin (5-HT)2C agonist, RO 60-0175: blockade of its actions by the novel 5-HT2C receptor antagonist SB 206,553. Millan, M.J., Girardon, S., Bervoets, K. Neuropharmacology (1997)
- Constitutive activity of the serotonin2C receptor inhibits in vivo dopamine release in the rat striatum and nucleus accumbens. De Deurwaerdère, P., Navailles, S., Berg, K.A., Clarke, W.P., Spampinato, U. J. Neurosci. (2004)
- Acute administration of amitriptyline and mianserin increases dopamine release in the rat nucleus accumbens: possible involvement of serotonin2C receptors. Di Matteo, V., Di Mascio, M., Di Giovanni, G., Esposito, E. Psychopharmacology (Berl.) (2000)
- Serotonin (5-HT) drugs: effects on appetite expression and use for the treatment of obesity. Halford, J.C., Harrold, J.A., Lawton, C.L., Blundell, J.E. Current drug targets. (2005)