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Chemical Compound Review:

AC1O52VP [(2R,3R,4R,5R,6R)-5-hydroxy- 6-[2-(4...

Synonyms:

Papoutsi, Z. et al., Abougazar, H. et al., Miao, J. et al., Liao, F. et al.

Miao, Wang, Yao, Navaratnam, Parson,

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High impact information on AIDS-112624

Martynoside was a potent antiestrogen in MCF-7 cells, increasing, like ICI182780, IGFBP3 levels via the ER-pathway [1].
In osteoblasts, martynoside induced nodule mineralization, which was abolished by ICI182780, implicating an ER-mediated mechanism [1].
Acteoside and martynoside antagonized both ERalpha and ERbeta (p<0.001), whereas they reversed the effect of E(2) mainly via ERalpha (p<0.001) [1].
From the aerial parts of Verbascum wiedemannianum Fisch. & Mey. four new phenylethanoid glycosides (wiedemanniosides B - E) were isolated along with four known compounds; 6- O-acetylmartynoside (= wiedemanniosides A), verbascoside, martynoside, echinacoside and leucosceptoside B [2].
Retardation of skeletal muscle fatigue by the two phenylpropanoid glycosides: verbascoside and martynoside from Pedicularis plicata maxim [3].

Analytical, diagnostic and therapeutic context of AIDS-112624

Free radical reactions of Martynoside (MAR), a phenylpropanoid glycoside, with a variety of oxidants were studied in the aqueous solution by laser photolysis and pulse radiolysis techniques [4].

References

Acteoside and martynoside exhibit estrogenic/antiestrogenic properties. Papoutsi, Z., Kassi, E., Mitakou, S., Aligiannis, N., Tsiapara, A., Chrousos, G.P., Moutsatsou, P. J. Steroid Biochem. Mol. Biol. (2006) [Pubmed]
Wiedemanniosides A-E: new phenylethanoid glycosides from the roots of Verbascum wiedemannianum. Abougazar, H., Bedir, E., Khan, I.A., Caliş, I. Planta Med. (2003) [Pubmed]
Retardation of skeletal muscle fatigue by the two phenylpropanoid glycosides: verbascoside and martynoside from Pedicularis plicata maxim. Liao, F., Zheng, R.L., Gao, J.J., Jia, Z.J. Phytotherapy research : PTR. (1999) [Pubmed]
Antioxidative properties of Martynoside: pulse radiolysis and laser photolysis study. Miao, J., Wang, W., Yao, S., Navaratnam, S., Parson, B.J. Free Radic. Res. (2003) [Pubmed]

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