Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Polyguacil [(2R,3S,4R,5R)-5-(2-amino-6- oxo-3H-purin-9...

Synonyms: AG-E-77001, Poly G-poly C, Poly(C.G), LS-73968, CTK8G2493, ...

Zhao, Y. et al., Shapir, E. et al.

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High impact information on Polyguacil

Several approaches were taken to measure mutational changes that occurred during the spaceflight including measurement of the integrity of poly-G/poly-C tracts, determination of the mutation frequency in the unc-22 gene, analysis of lethal mutations captured by the genetic balancer eT1(III;V), and identification of alterations in telomere length [1].

Analytical, diagnostic and therapeutic context of Polyguacil

High-resolution scanning tunneling microscopy (STM) imaging of single double-stranded poly(G)-poly(C) DNA molecules, made by a novel synthesis method, shows the molecules morphology [2].

References

A mutational analysis of Caenorhabditis elegans in space. Zhao, Y., Lai, K., Cheung, I., Youds, J., Tarailo, M., Tarailo, S., Rose, A. Mutat. Res. (2006) [Pubmed]
High-resolution STM imaging of novel poly(G)-poly(C) DNA molecules. Shapir, E., Cohen, H., Borovok, N., Kotlyar, A.B., Porath, D. The journal of physical chemistry. B, Condensed matter, materials, surfaces, interfaces & biophysical. (2006) [Pubmed]

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