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Chemical Compound Review:

SureCN21769 1-methylimidazolidine-2,4- dione

Synonyms: ACMC-1AZWK, M49887_ALDRICH, AG-K-61711, SureCN7217505, CHEBI:16354, ...

Esders, T.W. et al., Ogawa, J. et al., Möller, B. et al., Hermann, M. et al.

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Disease relevance of C02565

Creatinine iminohydrolase (EC 3.5.4.21), which catalyzes hydrolysis of creatinine to N-methylhydantoin and ammonia, was purified from Flavobacterium filamentosum [1].
Creatinine and N-methylhydantoin degradation in two newly isolated Clostridium species [2].
Purification and characterization of an ATP-dependent amidohydrolase, N-methylhydantoin amidohydrolase, from Pseudomonas putida 77 [3].

High impact information on C02565

Creatine was converted to N-methylhydantoin and with one species (Clostridium sordellii) to sarcosine in addition [4].

References

Purification and properties of creatinine iminohydrolase from Flavobacterium filamentosum. Esders, T.W., Lynn, S.Y. J. Biol. Chem. (1985) [Pubmed]
Creatinine and N-methylhydantoin degradation in two newly isolated Clostridium species. Hermann, M., Knerr, H.J., Mai, N., Gross, A., Kaltwasser, H. Arch. Microbiol. (1992) [Pubmed]
Purification and characterization of an ATP-dependent amidohydrolase, N-methylhydantoin amidohydrolase, from Pseudomonas putida 77. Ogawa, J., Kim, J.M., Nirdnoy, W., Amano, Y., Yamada, H., Shimizu, S. Eur. J. Biochem. (1995) [Pubmed]
Degradation of various amine compounds by mesophilic clostridia. Möller, B., Hippe, H., Gottschalk, G. Arch. Microbiol. (1986) [Pubmed]

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