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Chemical Compound Review:

Triiodobenzoic acid 2,3,5-triiodobenzoic acid

Synonyms: Johnkolor, Floraltone, TIBA, Regim 8, Regin 8, ...

Ho, J.X. et al., Fujita, H. et al., Lee, J.S. et al., Foster, C.M. et al., Kohita, H. et al., et al.

Foster, Horner, Graves,

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High impact information on Triiodobenzoic acid

Application of 2,3,5-triiodobenzoic acid, an inhibitor of polar transport of auxin, rescued postgermination phenotypes of young seedlings [1].
Only roots of control species that nodulate, Maackia amurensis Rupr. & Maxim. and alfalfa (Medicago sativa), produced pseudonodules after treatment with zeatin or 2,3,5-triiodobenzoic acid, an auxin transport inhibitor [2].
Treatment of maize or pea roots with inhibitors of auxin transport (morphactin, naphthylphthalamic acid, 2,3,5-triiodobenzoic acid) prevents both gravitropism and gravity-induced polar movement of calcium across the root tip [3].
Polar auxin transport inhibitors, including N-1-naphthylphthalamic acid (NPA) and 2,3,5-triiodobenzoic acid (TIBA), have various effects on physiological and developmental events, such as the elongation and tropism of roots and stems, in higher plants [4].
Crystallographic studies of equine serum albumin reveal two binding sites for 2,3,5-triiodobenzoic acid identical with those previously reported for human serum albumin which are located within subdomains in IIA and IIIA [5].

Associations of Triiodobenzoic acid with other chemical compounds

The displacement of the binding of CP to HSA and BSA was studied in the presence of phenylbutazone (PB, site I marker), ibuprofen (IB, site II marker) or 2,3,5-triiodobenzoic acid (TIB, both site I and II marker) [6].

Analytical, diagnostic and therapeutic context of Triiodobenzoic acid

The association constants (Ka) for the binding of 2,3,5-triiodobenzoic acid were determined by ultrafiltration methods for equine and human serum albumins to be approximately 10(4) M-1 and 10(5) M-1, respectively [5].

References

The polycotyledon mutant of tomato shows enhanced polar auxin transport. Al-Hammadi, A.S., Sreelakshmi, Y., Negi, S., Siddiqi, I., Sharma, R. Plant Physiol. (2003) [Pubmed]
Accumulation of ENOD2-like transcripts in non-nodulating woody papilionoid legumes. Foster, C.M., Horner, H.T., Graves, W.R. Plant Physiol. (2000) [Pubmed]
Inhibition of polar calcium movement and gravitropism in roots treated with auxin-transport inhibitors. Lee, J.S., Mulkey, T.J., Evans, M.L. Planta (1984) [Pubmed]
Genetic analysis of the effects of polar auxin transport inhibitors on root growth in Arabidopsis thaliana. Fujita, H., Syono, K. Plant Cell Physiol. (1996) [Pubmed]
X-ray and primary structure of horse serum albumin (Equus caballus) at 0.27-nm resolution. Ho, J.X., Holowachuk, E.W., Norton, E.J., Twigg, P.D., Carter, D.C. Eur. J. Biochem. (1993) [Pubmed]
Binding of carprofen to human and bovine serum albumins. Kohita, H., Matsushita, Y., Moriguchi, I. Chem. Pharm. Bull. (1994) [Pubmed]

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