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Chemical Compound Review

PubChem1692     1H-indole-3-carboxylic acid

Synonyms: SureCN64182, CHEMBL387527, ACMC-1BDYE, AG-B-83533, AG-G-73384, ...
 
 
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Disease relevance of MLS-0065969.P001

 

High impact information on MLS-0065969.P001

 

Biological context of MLS-0065969.P001

 

Gene context of MLS-0065969.P001

  • Synthesis and biological activity of a series of aryl tropanyl esters and amides chemically related to 1H-indole-3-carboxylic acid endo 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester. Development of a 5-HT4 agonist endowed with potent antinociceptive activity [10].

References

  1. Formation of indole-3-carboxylic acid by Chromobacterium violaceum. Davis, P.J., Gustafson, M.E., Rosazza, J.P. J. Bacteriol. (1976) [Pubmed]
  2. Cytotoxic and anti-HIV principles from the rhizomes of Begonia nantoensis. Wu, P.L., Lin, F.W., Wu, T.S., Kuoh, C.S., Lee, K.H., Lee, S.J. Chem. Pharm. Bull. (2004) [Pubmed]
  3. Universally occurring phenylpropanoid and species-specific indolic metabolites in infected and uninfected Arabidopsis thaliana roots and leaves. Tan, J., Bednarek, P., Liu, J., Schneider, B., Svatos, A., Hahlbrock, K. Phytochemistry (2004) [Pubmed]
  4. Pharmacokinetics and tissue disposition of indole-3-carbinol and its acid condensation products after oral administration to mice. Anderton, M.J., Manson, M.M., Verschoyle, R.D., Gescher, A., Lamb, J.H., Farmer, P.B., Steward, W.P., Williams, M.L. Clin. Cancer Res. (2004) [Pubmed]
  5. Identification of goat and mouse urinary metabolites of the pneumotoxin, 3-methylindole. Smith, D.J., Skiles, G.L., Appleton, M.L., Carlson, J.R., Yost, G.S. Xenobiotica (1993) [Pubmed]
  6. MDL 73,147EF, a 5-HT3 antagonist, facilitates latent inhibition in the rat. Moran, P.M., Moser, P.C. Pharmacol. Biochem. Behav. (1992) [Pubmed]
  7. Isolation and characterization of products from the nitrosation of the alkaloid gramine. Ahmad, M.U., Libbey, L.M., Barbour, J.F., Scanlan, R.A. Food Chem. Toxicol. (1985) [Pubmed]
  8. Cataractogenic effects in rats following chronic administration of SDZ ICT 322, a selective 5-HT3 antagonist. Längle, U.W., Wolf, A., Kammüller, M.E. Fundamental and applied toxicology : official journal of the Society of Toxicology. (1993) [Pubmed]
  9. The metabolism of tryptophan and 7-chlorotryptophan in Pseudomonas pyrrocinia and Pseudomonas aureofaciens. Lübbe, C., van Pée, K.H., Salcher, O., Lingens, F. Hoppe-Seyler's Z. Physiol. Chem. (1983) [Pubmed]
  10. Synthesis and biological activity of a series of aryl tropanyl esters and amides chemically related to 1H-indole-3-carboxylic acid endo 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester. Development of a 5-HT4 agonist endowed with potent antinociceptive activity. Romanelli, M.N., Ghelardini, C., Dei, S., Matucci, R., Mori, F., Scapecchi, S., Teodori, E., Bartolini, A., Galli, A., Giotti, A. Arzneimittel-Forschung. (1993) [Pubmed]
 
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