Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

D-serine (2R)-2-amino-3-hydroxy- propanoic acid

Synonyms: D-Serin, D-Ser, H-D-Ser-OH, AmbotzHAA1051, serine d-, ...

Sasabe, J. et al., Duffy, S. et al.

Steven Duffy, Viviane Labrie, John C. Roder,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Psychiatry related information on serine

D-serine may enhance a form of hippocampal NR2B-dependent LTD that contributes to spatial reversal learning [1].

Chemical compound and disease context of serine

Levels of D-Ser and its producing enzyme, serine racemase, in spinal cords of ALS mice were progressively elevated, dominantly in glia, with disease progression [2].

References

D-serine augments NMDA-NR2B receptor-dependent hippocampal long-term depression and spatial reversal learning. Duffy, S., Labrie, V., Roder, J.C. Neuropsychopharmacology (2008) [Pubmed]
D-serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosis. Sasabe, J., Chiba, T., Yamada, M., Okamoto, K., Nishimoto, I., Matsuoka, M., Aiso, S. EMBO J. (2007) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share