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Chemical Compound Review:

AC1LEJUD 4-methylbenzenecarbothioamide

Synonyms: CHEMBL285350, AG-E-69196, ACMC-20ameg, AC1Q7EFE, KB-72689, ...

Traiger, G.J. et al., Davidson, V.P. et al.

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Analytical, diagnostic and therapeutic context of p-Toluthioamide

Determination of p-methylthiobenzamide and p-methylthiobenzamide-S-oxide from rat plasma using solid-phase extraction and high-performance liquid chromatography [1].
Intraperitoneal injection of p-methylthiobenzamide (PMTB) to rats resulted in dose-dependent nephrotoxicity as judged by increased BUN levels, decreased TEA uptake and histologic examination of the kidney [2].

References

Determination of p-methylthiobenzamide and p-methylthiobenzamide-S-oxide from rat plasma using solid-phase extraction and high-performance liquid chromatography. Davidson, V.P., Traiger, G.J. J. Chromatogr. (1991) [Pubmed]
Nephrotoxicity of para-substituted thiobenzamide derivatives in the rat. Traiger, G.J., Gammal, L.M., Cox, D.N., Haschek, W.M. Toxicology (1989) [Pubmed]

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