Disease relevance of NSC 8897

• The subchronic toxicity of octyl acetate was assessed following its administration to rats via oral gavage, 5 days per week for 13 weeks [1].

Psychiatry related information on NSC 8897

• Because octyl acetate and octyl butyrate are characteristic of tissues consumed by the sixth instar, we investigated the influence of these esters on webworm feeding behavior and chemo-orientation [2].

High impact information on NSC 8897

• GC-MS analysis revealed that Atf1p and Atf2p are also responsible for the formation of a broad range of less volatile esters, such as propyl acetate, isobutyl acetate, pentyl acetate, hexyl acetate, heptyl acetate, octyl acetate, and phenyl ethyl acetate [3].
• Behavioural responses of Drosophila melanogaster larvae were measured in response to olfactory stimulation with an homologous series of eight aliphatic n-acetates (methyl ... octyl acetate) and with cis-vaccenyl acetate [4].
• The aliphatic esters octyl acetate and octyl butyrate occur as major components of essential oils in the vittae, or oil tubes, of the wild parsnip (Pastinaca sativa) [5].
• No octyl acetate was detected and the permeability of DMSO was proportional to its mole fraction in the mixture [6].
• Octyl acetate (CAS RN 108419-32-5) was administered via oral gavage to pregnant Sprague-Dawley rats on Gestation Days 6 through 15 at dose levels of 0, 0.1, 0.5, and 1.0 g/kg [7].

Analytical, diagnostic and therapeutic context of NSC 8897

• The interaction force between a rigid silica sphere and a butyl or octyl acetate droplet was measured in an aqueous environment using atomic force microscopy (AFM) [8].

References