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Chemical Compound Review:

Pemoline magnesium magnesium2-amino-5-phenyl- 1,3-oxazol-4...

Synonyms: Tamilan, Abbott 30400, LS-7190, DEA No. 1530, 10083-56-4, ...

This record was replaced with 4723.

Wilens, T.E. et al., Caresia, L. et al., Pratt, D.S. et al.

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Psychiatry related information on Phenoxazole

Pemoline (Cylert) is an agent used to treat attention deficit disorders and other behavioral syndromes [1].

High impact information on Phenoxazole

Because the stimulant medication magnesium pemoline (Cylert, Abbott Laboratories, Abbott Park, IL) has been found effective in treating ADHD in pediatric groups, we tested its efficacy in adults with ADHD using higher daily doses than those previously studied [2].

Analytical, diagnostic and therapeutic context of Phenoxazole

A clinical study has been conducted on a selected group of 9 children and 12 adults with attention deficit disorder, evaluating the response to the therapy with magnesium pemoline by means of EEG power spectra [3].

References

Hepatotoxicity due to pemoline (Cylert): a report of two cases. Pratt, D.S., Dubois, R.S. J. Pediatr. Gastroenterol. Nutr. (1990) [Pubmed]
Controlled trial of high doses of pemoline for adults with attention-deficit/hyperactivity disorder. Wilens, T.E., Biederman, J., Spencer, T.J., Frazier, J., Prince, J., Bostic, J., Rater, M., Soriano, J., Hatch, M., Sienna, M., Millstein, R.B., Abrantes, A. Journal of clinical psychopharmacology. (1999) [Pubmed]
EEG and clinical findings during pemoline treatment in children and adults with attention deficit disorder. An 8-week open trial. Caresia, L., Pugnetti, L., Besana, R., Barteselli, F., Guareschi Cazzullo, A., Musetti, L., Scarone, S. Neuropsychobiology (1984) [Pubmed]

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