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Chemical Compound Review:

Phlorone 2,5-dimethylcyclohexa-2,5- diene-1,4-dione

Synonyms: Floron, p-Xyloquinone, SureCN49964, AGN-PC-00GT3F, CHEMBL150457, ...

Floreani, M. et al., Zaborska, W. et al.

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High impact information on Phlorone

1,4-benzoquinone (BQ) and 2,5-dimethyl-1,4-benzoquinone (DMBQ) were studied as inhibitors of jack bean urease in 50 mM phosphate buffer, pH 7 [1].
1. Three benzoquinones (p-benzoquinone, 2,5-dimethyl-p-benzoquinone and tetramethyl-1,4-benzoquinone), differing for their electrophilicity, were tested on Ca2+ ATPase activity of cardiac sarcoplasmic reticulum membrane vesicles [2].

References

Inhibition of jack bean urease by 1,4-benzoquinone and 2,5-dimethyl-1,4-benzoquinone. Evaluation of the inhibition mechanism. Zaborska, W., Kot, M., Superata, K. Journal of enzyme inhibition and medicinal chemistry. (2002) [Pubmed]
Cardiac sarcoplasmic reticulum Ca2+ pump as a target for benzoquinones. Floreani, M., Forlin, A., Bellin, S., Carpenedo, F. Gen. Pharmacol. (1996) [Pubmed]

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