Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

CHEMBL157427 1,3-dichloropropane

Synonyms: NSC-6204, CCRIS 9220, D72204_ALDRICH, AG-D-83821, ANW-20690, ...

Tafazoli, M. et al., Tornero-Velez, R. et al.

Tornero-Velez, Ross, Granville, Laskey, Jones, DeMarini, Evans,

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Using rat liver microsomes and cytosol, we investigated the metabolism of two halopropanes found on the U.S. Environmental Protection Agency Contaminant Candidate List, 1,3-dichloropropane (1,3-DCP) and 2,2-dichloropropane (2,2-DCP) [1].
The mutagenicity and cytotoxicity of some of the candidate chemicals, namely 1,2-dichloroethylene, 1,1,2-trichloroethane, 1,3-dichloropropane, 1,2,3-trichloropropane and 1,1,3-trichloropropene were evaluated in an in vitro micronucleus assay [2].

References

Metabolism and mutagenicity of source water contaminants 1,3-dichloropropane and 2,2-dichloropropane. Tornero-Velez, R., Ross, M.K., Granville, C., Laskey, J., Jones, J.P., DeMarini, D.M., Evans, M.V. Drug Metab. Dispos. (2004) [Pubmed]
In vitro mutagenicity and genotoxicity study of 1,2-dichloroethylene, 1,1,2-trichloroethane, 1,3-dichloropropane, 1,2,3-trichloropropane and 1,1,3-trichloropropene, using the micronucleus test and the alkaline single cell gel electrophoresis technique (comet assay) in human lymphocytes. Tafazoli, M., Kirsch-Volders, M. Mutat. Res. (1996) [Pubmed]

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