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Chemical Compound Review

Githagenin     (4aS,6aR,6aS,6bR,8aR,9S,10S,12 aS,14bR)-10...

Synonyms: Gypsogenin, Albsapogenin, albasapogenin, CHEBI:5580, AC1L3OWV, ...
 
 
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High impact information on Astrantiagenin D

  • Plants of the genus Gypsophila (Caryophyllaceae) are important industrially because of the capacity of their saponin constituents to behave like natural detergents.1 Saponins from this genus are based on oleanolic acid (3-hydroxyolean-12-en-28-oic acid), with gypsogenin being the main pentacyclic triterpenoidal aglycon found [1].
  • Analysis of bisdesmosidic saponins in Saponaria vaccaria L. by HPLC-PAD-MS: identification of new quillaic acid and gypsogenin 3-O-trisaccharides [2].
  • A new triterpenoid saponin was isolated from the roots of Silene cucubalus and its structure was determined on the basis of one- and two-dimensional NMR spectroscopy as gypsogenin 3-O-beta-xylopyranosyl-(1-->3)-[beta-galactopyranosyl-(1-->2)]-beta-glucuronopyranoside [3].

References

  1. Two new sulfated saponins from the roots of Gypsophila bermejoi. Acebes, B., Bernabé, M., Díaz-Lanza, A.M., Bartolomé, C. J. Nat. Prod. (1998) [Pubmed]
  2. Analysis of bisdesmosidic saponins in Saponaria vaccaria L. by HPLC-PAD-MS: identification of new quillaic acid and gypsogenin 3-O-trisaccharides. Balsevich, J.J., Bishop, G.G., Ramirez-Erosa, I. Phytochemical analysis : PCA (2006) [Pubmed]
  3. Triterpenoid saponins from the roots of Silene cucubalus. Larhsini, M., Marston, A., Hostettmann, K. Fitoterapia (2003) [Pubmed]
 
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